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Male reproductive disorders and fertility trends: influences of environment and genetic susceptibility
NE Skakkebaek, E Rajpert-De Meyts… - Physiological …, 2016 - journals.physiology.org
It is predicted that Japan and European Union will soon experience appreciable decreases
in their populations due to persistently low total fertility rates (TFR) below replacement level …
in their populations due to persistently low total fertility rates (TFR) below replacement level …
Human germ cell tumours from a developmental perspective
JW Oosterhuis, LHJ Looijenga - Nature Reviews Cancer, 2019 - nature.com
Human germ cell tumours (GCTs) are derived from stem cells of the early embryo and the
germ line. They occur in the gonads (ovaries and testes) and also in extragonadal sites …
germ line. They occur in the gonads (ovaries and testes) and also in extragonadal sites …
Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells
EJ Grow, RA Flynn, SL Chavez, NL Bayless… - Nature, 2015 - nature.com
Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections, and comprise
nearly 8% of the human genome. The most recently acquired human ERV is HERVK (HML …
nearly 8% of the human genome. The most recently acquired human ERV is HERVK (HML …
Testicular germ cell tumours
E Rajpert-De Meyts, KA McGlynn, K Okamoto… - The Lancet, 2016 - thelancet.com
Testicular germ cell tumours are at the crossroads of developmental and neoplastic
processes. Their cause has not been fully elucidated but differences in incidences suggest …
processes. Their cause has not been fully elucidated but differences in incidences suggest …
Systematic discovery and characterization of regulatory motifs in ENCODE TF binding experiments
P Kheradpour, M Kellis - Nucleic acids research, 2014 - academic.oup.com
Recent advances in technology have led to a dramatic increase in the number of available
transcription factor ChIP-seq and ChIP-chip data sets. Understanding the motif content of …
transcription factor ChIP-seq and ChIP-chip data sets. Understanding the motif content of …
[HTML][HTML] Role of OCT4 in cancer stem-like cells and chemotherapy resistance
IS Mohiuddin, SJ Wei, MH Kang - … Acta (BBA)-Molecular Basis of Disease, 2020 - Elsevier
Cancer stem-like cells (CSCs) contribute to the tumorigenicity, progression, and
chemoresistance of cancers. It is not known whether CSCs arise from normal stem cells or if …
chemoresistance of cancers. It is not known whether CSCs arise from normal stem cells or if …
Human dental pulp stem cells: Applications in future regenerative medicine
PD Potdar, YD Jethmalani - World journal of stem cells, 2015 - pmc.ncbi.nlm.nih.gov
Stem cells are pluripotent cells, having a property of differentiating into various types of cells
of human body. Several studies have developed mesenchymal stem cells (MSCs) from …
of human body. Several studies have developed mesenchymal stem cells (MSCs) from …
[HTML][HTML] Testicular cancer: Determinants of cisplatin sensitivity and novel therapeutic opportunities
G de Vries, X Rosas-Plaza, MATM van Vugt… - Cancer Treatment …, 2020 - Elsevier
Testicular cancer (TC) is the most common solid tumor among men aged between 15 and
40 years. TCs are highly aneuploid and the 12p isochromosome is the most frequent …
40 years. TCs are highly aneuploid and the 12p isochromosome is the most frequent …
[HTML][HTML] The 2015 World Health Organization classification of tumors of the thymus: continuity and changes
A Marx, JKC Chan, JM Coindre, F Detterbeck… - Journal of Thoracic …, 2015 - Elsevier
This overview of the 4th edition of the World Health Organization (WHO) Classification of
thymic tumors has two aims. First, to comprehensively list the established and new tumor …
thymic tumors has two aims. First, to comprehensively list the established and new tumor …
Testicular germ-cell tumours in a broader perspective
JW Oosterhuis, LHJ Looijenga - Nature Reviews Cancer, 2005 - nature.com
The germ-cell tumours are a fascinating group of neoplasms because of their unusual
biology and the spectacular therapeutic results that have been obtained in these tumours …
biology and the spectacular therapeutic results that have been obtained in these tumours …