Breast cancer—a heterogeneous disease marked with a high mortality rate, necessitates
early diagnosis and treatment. The availability of multi-omic data has revolutionized our …

Pyroptosis is a form of regulated cell death mediated by the gasdermin protein family. During
virus infection, cell pyroptosis restricts viral replication. The mechanisms of the tripartite motif …

The steroidal alkaloid tomatidine is an aglycone of α-tomatine, which is abundant in tomato
leaves and has several biological activities. Tomatidine has been reported to inhibit the …

Simple Summary Chemerin is a multifunctional protein with an important role in the immune
system. Recent evidence showed that chemerin also regulates the development of cancer …

A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAMTS16) has been
reported to be involved in the pathogenesis of solid cancers. However, its role in gastric …

Epithelial splicing regulatory proteins 1 and 2 (ESRP1/2) control the splicing pattern during
epithelial to mesenchymal transition (EMT) in a physiological context and in cancer …

Simple Summary Chemoimmunotherapy combinations have transformed the treatment
landscape for patients with triple-negative breast cancer (TNBC). However, the discovery of …

This work is performed to investigate the effect of coptisine (COP) on the malignant
biological behaviors of bladder carcinoma cells and its underlying mechanism. Bladder …

Simple Summary Interferon alpha (IFNα) signaling is highly upregulated in ER+ breast
cancers that become resistant to estrogen deprivation therapy. This study uncovers how …

Breast cancer expressing the estrogen receptor (ER), progesterone receptor (PR) and
human epidermal growth factor receptor-2 (HER2) is known as triple-positive (TPBC). TPBC …