Archaea are diverse, ecologically important, single-celled microorganisms. They have
unique functions and features, such as methanogenesis and the composition of their cell …

The tree of life shows the relationship between all organisms based on their common
ancestry. Until 1977, it comprised two major branches: prokaryotes and eukaryotes. Work by …

Speciation of sexually reproducing organisms requires reproductive barriers. Prokaryotes
reproduce asexually but often exchange DNA by lateral gene transfer mechanisms and …

Prasinoviruses infecting unicellular green algae in the order Mamiellales (class
Mamiellophyceae) are commonly found in coastal marine waters where their host species …

Despite the advent of next-generation sequencing (NGS) technologies, sophisticated data
analysis and drug development efforts, bacterial drug resistance persists and is escalating in …

Inteins are parasitic genetic elements that excise themselves at the protein level by self-
splicing, allowing the formation of functional, nondisrupted proteins. Many inteins contain a …

The model haloarchaeon Haloferax volcanii is polyploid with about 20 copies of its major
chromosome. Recently it has been described that highly efficient intermolecular gene …

An intein from Halobacterium salinarum can be isolated as an unspliced precursor protein
with exogenous exteins after Escherichia coli overexpression. The intein promotes protein …

In recent years, both homing endonucleases (HEases) and zinc-finger nucleases (ZFNs)
have been engineered and selected for the targeting of desired human loci for gene therapy …

Inteins are selfish genetic elements that disrupt the sequence of protein-coding genes and
are excised post-translationally. Most inteins also contain a HEN (homing endonuclease) …