[HTML][HTML] The methods of choice for extracellular vesicles (EVs) characterization

R Szatanek, M Baj-Krzyworzeka, J Zimoch… - International journal of …, 2017‏ - mdpi.com
In recent years, extracellular vesicles (EVs) have become a subject of intense study. These
membrane-enclosed spherical structures are secreted by almost every cell type and are …

Inside (sight) of tiny communicator: exosome biogenesis, secretion, and uptake

AS Jadli, N Ballasy, P Edalat, VB Patel - Molecular and cellular …, 2020‏ - Springer
Discovered in the late 1980s as an extracellular vesicle of endosomal origin secreted from
reticulocytes, exosomes recently gained scientific attention due to its role in intercellular …

Modification of extracellular vesicles by fusion with liposomes for the design of personalized biogenic drug delivery systems

M Piffoux, AKA Silva, C Wilhelm, F Gazeau, D Tareste - ACS nano, 2018‏ - ACS Publications
Extracellular vesicles (EVs) are recognized as nature's own carriers to transport
macromolecules throughout the body. Hijacking this endogenous communication system …

Exosomes in bodily fluids are a highly stable resource of disease biomarkers

S Boukouris, S Mathivanan - PROTEOMICS–Clinical …, 2015‏ - Wiley Online Library
Biomarkers are measurable indicators of a biological state. As our understanding of
diseases meliorates, it is generally accepted that early diagnosis renders the best chance to …

[HTML][HTML] Extracellular vesicles from blood plasma: determination of their morphology, size, phenotype and concentration

N Arraud, R Linares, S Tan, C Gounou… - Journal of Thrombosis …, 2014‏ - Elsevier
Background Plasma and other body fluids contain membranous extracellular vesicles (EVs),
which are considered to derive from activated or apoptotic cells. EVs participate in …

Extracellular vesicles in renal disease

D Karpman, A Ståhl, I Arvidsson - Nature Reviews Nephrology, 2017‏ - nature.com
Extracellular vesicles, such as exosomes and microvesicles, are host cell-derived packages
of information that allow cell–cell communication and enable cells to rid themselves of …

Oxidative stress and antioxidants in hypertension–a current review

N Sinha, P Kumar Dabla - Current hypertension reviews, 2015‏ - benthamdirect.com
Free radicals or reactive oxygen species (ROS) are generated by oxygen metabolism which
is balanced by the rate of oxidant formation and the rate of oxidant elimination. Oxidative …

Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease?

EE Creemers, AJ Tijsen, YM Pinto - Circulation research, 2012‏ - ahajournals.org
In the past few years, the crucial role of different micro-RNAs (miRNAs) in the cardiovascular
system has been widely recognized. Recently, it was discovered that extracellular miRNAs …

Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection

A Zernecke, K Bidzhekov, H Noels, E Shagdarsuren… - Science …, 2009‏ - science.org
Apoptosis is a pivotal process in embryogenesis and postnatal cell homeostasis and
involves the shedding of membranous microvesicles termed apoptotic bodies. In response …

Novel biomarkers for evaluation of endothelial dysfunction

AR Leite, M Borges-Canha, R Cardoso… - …, 2020‏ - journals.sagepub.com
Endothelial dysfunction is one of the earliest indicators of cardiovascular (CV) dysfunction,
and its evaluation would be of considerable importance to stratify CV risk of many diseases …