Cryopreservation of cells and biologics underpins all biomedical research from routine
sample storage to emerging cell-based therapies, as well as ensuring cell banks provide …

In nature, many biological organisms have developed the exceptional antifreezing ability to
survive in extremely cold environments. Inspired by the freeze resistance of these …

Polyampholytes are emerging macromolecular membrane non-penetrating cryoprotectants;
however, the mechanism behind their cryopreservation remains unclear. Here, we …

The storage and transport of cells is a fundamental technology which underpins cell biology,
biomaterials research, and emerging cell-based therapies. Inspired by antifreeze and ice …

Cellular cryopreservation is a platform technology which underpins cell biology,
biochemistry, biomaterials, diagnostics, and the cold chain for emerging cell-based …

Cryopreservation is a process used for the storage of mammalian cells at a very low
temperature, in a state of 'suspended animation.'Highly effective and safe macromolecular …

Dimethyl sulfoxide (DMSO) is widely used as a solvent in the life sciences, however, it is
somewhat toxic and affects cell behaviours in a range of ways. Here, we propose a …

Spheroids are a powerful tool for basic research and to reduce or replace in vivo (animal)
studies but are not routinely banked nor shared. Here, we report the successful …

The cryopreservation of cells underpins many areas of biotechnology, healthcare, and
fundamental science by enabling the banking and distribution of cells. Cryoprotectants are …

Cryopreservation has been a key technology in medical science, food preservation, and
many other fields. In a freezing process, the formation of ice crystals may cause significant …