High-sensitivity analytical approaches for the structural characterization of glycoproteins

WR Alley Jr, BF Mann, MV Novotny - Chemical reviews, 2013 - ACS Publications
1.1. General Considerations Structural intricacies of carbohydrate molecules and their
propensity to form varied linkages, substitutions, and branching patterns have fascinated …

The sweet tooth of bacteria: common themes in bacterial glycoconjugates

HLP Tytgat, S Lebeer - Microbiology and Molecular Biology …, 2014 - Am Soc Microbiol
Humans have been increasingly recognized as being superorganisms, living in close
contact with a microbiota on all their mucosal surfaces. However, most studies on the human …

Sweet talk: protein glycosylation in bacterial interaction with the host

Q Lu, S Li, F Shao - Trends in Microbiology, 2015 - cell.com
Pathogenic bacteria encode virulent glycosyltransferases that conjugate various glycans
onto substrate proteins via the N-or O-linkage. The HMW system in nontypeable …

Pour some sugar on it: the expanding world of bacterial protein O‐linked glycosylation

JA Iwashkiw, NF Vozza, RL Kinsella… - Molecular …, 2013 - Wiley Online Library
Protein glycosylation was once considered as an eccentricity of a few bacteria. However in
the recent years multiple O‐glycosylation mechanisms have been identified in bacterial …

Acinetobacter strains carry two functional oligosaccharyltransferases, one devoted exclusively to type IV pilin, and the other one dedicated to O‐glycosylation of …

CM Harding, MA Nasr, RL Kinsella… - Molecular …, 2015 - Wiley Online Library
Multiple species within the A cinetobacter genus are nosocomial opportunistic pathogens of
increasing relevance worldwide. Among the virulence factors utilized by these bacteria are …

From the Outside-In: The Francisella tularensis Envelope and Virulence

HM Rowe, JF Huntley - Frontiers in cellular and infection microbiology, 2015 - frontiersin.org
Francisella tularensis is a highly-infectious bacterium that causes the rapid, and often lethal
disease, tularemia. Many studies have been performed to identify and characterize the …

Francisella tularensis Outer Membrane Vesicles Participate in the Early Phase of Interaction With Macrophages

I Pavkova, J Klimentova, J Bavlovic… - Frontiers in …, 2021 - frontiersin.org
Francisella tularensis is known to release unusually shaped tubular outer membrane
vesicles (OMV) containing a number of previously identified virulence factors and …

Uncovering the components of the Francisella tularensis virulence stealth strategy

BD Jones, M Faron, JA Rasmussen… - Frontiers in cellular and …, 2014 - frontiersin.org
Over the last decade, studies on the virulence of the highly pathogenic intracellular bacterial
pathogen Francisella tularensis have increased dramatically. The organism produces an …

A general protein O‐glycosylation system within the Burkholderia cepacia complex is involved in motility and virulence

KV Lithgow, NE Scott, JA Iwashkiw… - Molecular …, 2014 - Wiley Online Library
Bacteria of the B urkholderia cepacia complex (Bcc) are pathogens of humans, plants, and
animals. B urkholderia cenocepacia is one of the most common Bcc species infecting cystic …

The post‐translational modification of the Clostridium difficile flagellin affects motility, cell surface properties and virulence

A Faulds‐Pain, SM Twine, E Vinogradov… - Molecular …, 2014 - Wiley Online Library
C lostridium difficile is a prominent nosocomial pathogen, proliferating and causing enteric
disease in individuals with a compromised gut microflora. We characterized the post …