High-sensitivity analytical approaches for the structural characterization of glycoproteins
1.1. General Considerations Structural intricacies of carbohydrate molecules and their
propensity to form varied linkages, substitutions, and branching patterns have fascinated …
propensity to form varied linkages, substitutions, and branching patterns have fascinated …
The sweet tooth of bacteria: common themes in bacterial glycoconjugates
Humans have been increasingly recognized as being superorganisms, living in close
contact with a microbiota on all their mucosal surfaces. However, most studies on the human …
contact with a microbiota on all their mucosal surfaces. However, most studies on the human …
Sweet talk: protein glycosylation in bacterial interaction with the host
Pathogenic bacteria encode virulent glycosyltransferases that conjugate various glycans
onto substrate proteins via the N-or O-linkage. The HMW system in nontypeable …
onto substrate proteins via the N-or O-linkage. The HMW system in nontypeable …
Pour some sugar on it: the expanding world of bacterial protein O‐linked glycosylation
JA Iwashkiw, NF Vozza, RL Kinsella… - Molecular …, 2013 - Wiley Online Library
Protein glycosylation was once considered as an eccentricity of a few bacteria. However in
the recent years multiple O‐glycosylation mechanisms have been identified in bacterial …
the recent years multiple O‐glycosylation mechanisms have been identified in bacterial …
Acinetobacter strains carry two functional oligosaccharyltransferases, one devoted exclusively to type IV pilin, and the other one dedicated to O‐glycosylation of …
Multiple species within the A cinetobacter genus are nosocomial opportunistic pathogens of
increasing relevance worldwide. Among the virulence factors utilized by these bacteria are …
increasing relevance worldwide. Among the virulence factors utilized by these bacteria are …
From the Outside-In: The Francisella tularensis Envelope and Virulence
Francisella tularensis is a highly-infectious bacterium that causes the rapid, and often lethal
disease, tularemia. Many studies have been performed to identify and characterize the …
disease, tularemia. Many studies have been performed to identify and characterize the …
Francisella tularensis Outer Membrane Vesicles Participate in the Early Phase of Interaction With Macrophages
I Pavkova, J Klimentova, J Bavlovic… - Frontiers in …, 2021 - frontiersin.org
Francisella tularensis is known to release unusually shaped tubular outer membrane
vesicles (OMV) containing a number of previously identified virulence factors and …
vesicles (OMV) containing a number of previously identified virulence factors and …
Uncovering the components of the Francisella tularensis virulence stealth strategy
BD Jones, M Faron, JA Rasmussen… - Frontiers in cellular and …, 2014 - frontiersin.org
Over the last decade, studies on the virulence of the highly pathogenic intracellular bacterial
pathogen Francisella tularensis have increased dramatically. The organism produces an …
pathogen Francisella tularensis have increased dramatically. The organism produces an …
A general protein O‐glycosylation system within the Burkholderia cepacia complex is involved in motility and virulence
KV Lithgow, NE Scott, JA Iwashkiw… - Molecular …, 2014 - Wiley Online Library
Bacteria of the B urkholderia cepacia complex (Bcc) are pathogens of humans, plants, and
animals. B urkholderia cenocepacia is one of the most common Bcc species infecting cystic …
animals. B urkholderia cenocepacia is one of the most common Bcc species infecting cystic …
The post‐translational modification of the Clostridium difficile flagellin affects motility, cell surface properties and virulence
A Faulds‐Pain, SM Twine, E Vinogradov… - Molecular …, 2014 - Wiley Online Library
C lostridium difficile is a prominent nosocomial pathogen, proliferating and causing enteric
disease in individuals with a compromised gut microflora. We characterized the post …
disease in individuals with a compromised gut microflora. We characterized the post …