CaMKII as a therapeutic target in cardiovascular disease

OE Reyes Gaido, LJ Nkashama… - Annual review of …, 2023 - annualreviews.org
CaMKII (the multifunctional Ca2+ and calmodulin-dependent protein kinase II) is a highly
validated signal for promoting a variety of common diseases, particularly in the …

Advances and challenges in cell biology for cultured meat

B Martins, A Bister, RGJ Dohmen… - Annual review of …, 2024 - annualreviews.org
Cultured meat is an emerging biotechnology that aims to produce meat from animal cell
culture, rather than from the raising and slaughtering of livestock, on environmental and …

Molecular mechanisms underlying the impact of muscle fiber types on meat quality in livestock and poultry

M Mo, Z Zhang, X Wang, W Shen, L Zhang… - Frontiers in Veterinary …, 2023 - frontiersin.org
In the past, the primary emphasis of livestock and poultry breeding was mainly on improving
the growth rate, meat production efficiency and disease resistance. However, the …

Ageing of skeletal muscle extracellular matrix and mitochondria: Finding a potential link

L Cai, L Shi, Z Peng, Y Sun, J Chen - Annals of Medicine, 2023 - Taylor & Francis
Aim: To discuss the progress of extracellular matrix (ECM) characteristics, mitochondrial
homeostasis, and their potential crosstalk in the pathogenesis of sarcopenia, a geriatric …

Continuous fish muscle cell line with capacity for myogenic and adipogenic-like phenotypes

MK Saad, JSK Yuen Jr, CM Joyce, X Li, T Lim… - Scientific Reports, 2023 - nature.com
Cell-cultivated fish offers the potential for a more ethical, sustainable, and safe seafood
system. However, fish cell culture is relatively understudied in comparison to mammalian …

Regulation of the myoblast fusion reaction for muscle development, regeneration, and adaptations

DP Millay - Experimental cell research, 2022 - Elsevier
Fusion of plasma membranes is essential for skeletal muscle development, regeneration,
exercise-induced adaptations, and results in a cell that contains hundreds to thousands of …

Growing meat on autoclaved vegetables with biomimetic stiffness and micro-patterns

Y Liu, A Gao, T Wang, Y Zhang, G Zhu, S Ling… - Nature …, 2025 - nature.com
Cultured meat needs edible bio-scaffolds that provide not only a growth milieu for muscle
and adipose cells, but also biomimetic stiffness and tissue-sculpting topography. Current …

The TAS1R2 G-protein-coupled receptor is an ambient glucose sensor in skeletal muscle that regulates NAD homeostasis and mitochondrial capacity

J Serrano, J Boyd, IS Brown, C Mason… - Nature …, 2024 - nature.com
The bioavailability of nicotinamide adenine dinucleotide (NAD) is vital for skeletal muscle
health, yet the mechanisms or signals regulating NAD homeostasis remain unclear. Here …

[HTML][HTML] Livestock cell types with myogenic differentiation potential: considerations for the development of cultured meat

M Olenic, C Deelkens, E Heyman, E De Vlieghere… - animal, 2024 - Elsevier
With the current environmental impact of large-scale animal production and societal
concerns about welfare of farm animals, researchers are questioning whether we can …

Carbon dioxide regulates cholesterol levels through SREBP2

N Bolshette, S Ezagouri, V Dandavate, I Karavaeva… - PLoS …, 2023 - journals.plos.org
In mammals, O2 and CO2 levels are tightly regulated and are altered under various
pathological conditions. While the molecular mechanisms that participate in O2 sensing are …