Bone tissue engineering in the treatment of bone defects

N Xue, X Ding, R Huang, R Jiang, H Huang, X Pan… - Pharmaceuticals, 2022 - mdpi.com
Bones play an important role in maintaining exercise and protecting organs. Bone defect, as
a common orthopedic disease in clinics, can cause tremendous damage with long treatment …

The crosstalk of adipose-derived stem cells (ADSC), oxidative stress, and inflammation in protective and adaptive responses

L Rochette, L Mazini, G Malka, M Zeller… - International journal of …, 2020 - mdpi.com
The potential use of stem cell-based therapies for the repair and regeneration of various
tissues and organs is a major goal in repair medicine. Stem cells are classified by their …

[HTML][HTML] Cell-adaptable dynamic hydrogel reinforced with stem cells improves the functional repair of spinal cord injury by alleviating neuroinflammation

X Yuan, W Yuan, L Ding, M Shi, L Luo, Y Wan, J Oh… - Biomaterials, 2021 - Elsevier
Spinal cord injury (SCI) is one of the most challenging clinical issues. It is characterized by
the disruption of neural circuitry and connectivity, resulting in neurological disability. Adipose …

Unveiling therapeutic potential: Adipose tissue-derived mesenchymal stem cells and their exosomes in the management of diabetes mellitus, wound healing, and …

A Ahmadieh-Yazdi, M Karimi, E Afkhami… - Biochemical …, 2024 - Elsevier
Diabetes mellitus (DM) is a pervasive global health issue with substantial morbidity and
mortality, often resulting in secondary complications, including diabetic wounds (DWs) …

Skin immunomodulation during regeneration: emerging new targets

L Mazini, L Rochette, Y Hamdan, G Malka - Journal of personalized …, 2021 - mdpi.com
Adipose-Derived Stem Cells (ADSC) are present within the hypodermis and are also
expected to play a pivotal role in wound healing, immunomodulation, and rejuvenation …

Artificial Nanovesicles Derived from Cells: A Promising Alternative to Extracellular Vesicles

S Lou, W Hu, P Wei, D He, P Fu, K Ding… - … Applied Materials & …, 2024 - ACS Publications
As naturally secreted vesicles by cells, extracellular vesicles (EVs) play essential roles in
modulating cell–cell communication and have significant potential in tissue regeneration …

Therapeutic potential of mesenchymal stem cells in the treatment of epilepsy and their interaction with antiseizure medications

MR Tesiye, M Gol, MR Fadardi, SNM Kani, AM Costa… - Cells, 2022 - mdpi.com
Epilepsy is a life-threatening neurological disease that affects approximately 70 million
people worldwide. Although the vast majority of patients may be successfully managed with …

lncRNA‐KCNQ1OT1: A Potential Target in Exosomes Derived from Adipose‐Derived Stem Cells for the Treatment of Osteoporosis

S Wang, J Jia, C Chen - Stem Cells International, 2021 - Wiley Online Library
Background. Osteoporosis is a worldwide medical and socioeconomic burden characterized
by systemic impairment of bone strength and microstructure. Exosomes derived from …

Fat grafting as regenerative surgery: a current review

JM Firriolo, A Condé-Green, LLQ Pu - Plastic and Reconstructive …, 2022 - journals.lww.com
Autologous fat grafting has long been regarded as an ideal filler, lauded for its ability to
restore soft-tissue contour. In recent times, fat grafting has exhibited regenerative capacity …

GREM1 inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells

H Liu, X Han, H Yang, Y Cao, C Zhang… - Connective tissue …, 2021 - Taylor & Francis
Purpose: Adipose-derived stem cells (ADSCs) are ideal for cell-based therapies to support
bone regeneration. It is vital to understand the critical genes and molecular mechanisms …