[HTML][HTML] Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria
Antimicrobial resistance has been a global health challenge that threatens our ability to
control and treat life-threatening bacterial infections. Despite ongoing efforts to identify new …
control and treat life-threatening bacterial infections. Despite ongoing efforts to identify new …
β-lactam Resistance in Pseudomonas aeruginosa: Current Status, Future Prospects
KA Glen, IL Lamont - Pathogens, 2021 - mdpi.com
Pseudomonas aeruginosa is a major opportunistic pathogen, causing a wide range of acute
and chronic infections. β-lactam antibiotics including penicillins, carbapenems …
and chronic infections. β-lactam antibiotics including penicillins, carbapenems …
Efflux pump inhibitors of clinically relevant multidrug resistant bacteria
Bacterial infections are an increasingly serious issue worldwide. The inability of existing
therapies to treat multidrug‐resistant pathogens has been recognized as an important …
therapies to treat multidrug‐resistant pathogens has been recognized as an important …
Similarities and differences between silver ions and silver in nanoforms as antibacterial agents
A Kędziora, M Speruda, E Krzyżewska, J Rybka… - International journal of …, 2018 - mdpi.com
Silver is considered as antibacterial agent with well-known mode of action and bacterial
resistance against it is well described. The development of nanotechnology provided …
resistance against it is well described. The development of nanotechnology provided …
Multidrug efflux pumps at the crossroad between antibiotic resistance and bacterial virulence
Multidrug efflux pumps can be involved in bacterial resistance to antibiotics at different
levels. Some efflux pumps are constitutively expressed at low levels and contribute to …
levels. Some efflux pumps are constitutively expressed at low levels and contribute to …
[HTML][HTML] Esca** mechanisms of ESKAPE pathogens from antibiotics and their targeting by natural compounds
R Jadimurthy, SB Mayegowda, SC Nayak… - Biotechnology …, 2022 - Elsevier
The microorganisms that have developed resistance to available therapeutic agents are
threatening the globe and multidrug resistance among the bacterial pathogens is becoming …
threatening the globe and multidrug resistance among the bacterial pathogens is becoming …
Distribution and spread of the mobilised RND efflux pump gene cluster tmexCD-toprJ in clinical Gram-negative bacteria: a molecular epidemiological study
N Dong, Y Zeng, Y Wang, C Liu, J Lu, C Cai… - The Lancet …, 2022 - thelancet.com
Summary Background TMexCD1-TOprJ1, which is associated with phenotypic resistance to
multiple classes of antibiotics, is a transmissible resistance-nodulation-division (RND) family …
multiple classes of antibiotics, is a transmissible resistance-nodulation-division (RND) family …
RND efflux pumps in Gram-negative bacteria; regulation, structure and role in antibiotic resistance
AL Colclough, I Alav, EE Whittle, HL Pugh… - Future …, 2020 - Taylor & Francis
Rresistance-nodulation-division (RND) efflux pumps in Gram-negative bacteria remove
multiple, structurally distinct classes of antimicrobials from inside bacterial cells therefore …
multiple, structurally distinct classes of antimicrobials from inside bacterial cells therefore …
Triclosan: Antimicrobial mechanisms, antibiotics interactions, clinical applications, and human health
P Shrestha, Y Zhang, WJ Chen… - Journal of Environmental …, 2020 - Taylor & Francis
The large-scale applications of Triclosan in industrial and household products have created
many health and environmental concerns. Despite the fears of its drug-resistance and other …
many health and environmental concerns. Despite the fears of its drug-resistance and other …
The balance between antibiotic resistance and fitness/virulence in Pseudomonas aeruginosa: an update on basic knowledge and fundamental research
E Jordana-Lluch, IM Barceló… - Frontiers in …, 2023 - frontiersin.org
The interplay between antibiotic resistance and bacterial fitness/virulence has attracted the
interest of researchers for decades because of its therapeutic implications, since it is …
interest of researchers for decades because of its therapeutic implications, since it is …