Oxidative stress: The core pathogenesis and mechanism of Alzheimer's disease

R Bai, J Guo, XY Ye, Y **e, T **e - Ageing research reviews, 2022 - Elsevier
As the number of patients with Alzheimer's disease (AD) increases, it brings great suffering
to their families and causes a heavy socioeconomic burden to society. A vast amount of …

Oxidative stress and beta amyloid in Alzheimer's disease. Which comes first: the chicken or the egg?

E Tamagno, M Guglielmotto, V Vasciaveo, M Tabaton - Antioxidants, 2021 - mdpi.com
The pathogenesis of Alzheimer's disease involves β amyloid (Aβ) accumulation known to
induce synaptic dysfunction and neurodegeneration. The brain's vulnerability to oxidative …

Oxidative stress in Alzheimer's disease

Z Chen, C Zhong - Neuroscience bulletin, 2014 - Springer
Oxidative stress plays a significant role in the pathogenesis of Alzheimer's disease (AD), a
devastating disease of the elderly. The brain is more vulnerable than other organs to …

Oxidative stress and the pathogenesis of Alzheimer′ s disease

Y Zhao, B Zhao - Oxidative medicine and cellular longevity, 2013 - Wiley Online Library
Alzheimer′ s disease (AD) is the most common neurodegenerative disease that causes
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …

Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and Parkinson's disease

G Ganguly, S Chakrabarti, U Chatterjee… - Drug design …, 2017 - Taylor & Francis
Alzheimer's disease and Parkinson's disease are two common neurodegenerative diseases
of the elderly people that have devastating effects in terms of morbidity and mortality. The …

PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer's disease

F Du, Q Yu, S Yan, G Hu, LF Lue, DG Walker, L Wu… - Brain, 2017 - academic.oup.com
Mitochondrial dysfunction and synaptic damage are early pathological features of the
Alzheimer's disease-affected brain. Memory impairment in Alzheimer's disease is a …

Bioinorganic chemistry of Alzheimer's disease

KP Kepp - Chemical reviews, 2012 - ACS Publications
Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …

Smoking and increased Alzheimer's disease risk: a review of potential mechanisms

TC Durazzo, N Mattsson, MW Weiner… - Alzheimer's & …, 2014 - Wiley Online Library
Background Cigarette smoking has been linked with both increased and decreased risk for
Alzheimer's disease (AD). This is relevant for the US military because the prevalence of …

Molecular mechanisms and genetics of oxidative stress in Alzheimer's disease

F Cioffi, RHI Adam, K Broersen - Journal of Alzheimer's …, 2019 - content.iospress.com
Alzheimer's disease is the most common neurodegenerative disorder that can cause
dementia in elderly over 60 years of age. One of the disease hallmarks is oxidative stress …

Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease?

VE Johnson, W Stewart, DH Smith - Nature Reviews Neuroscience, 2010 - nature.com
Traumatic brain injury (TBI) has devastating acute effects and in many cases seems to
initiate long-term neurodegeneration. Indeed, an epidemiological association between TBI …