Oxidative stress: The core pathogenesis and mechanism of Alzheimer's disease
As the number of patients with Alzheimer's disease (AD) increases, it brings great suffering
to their families and causes a heavy socioeconomic burden to society. A vast amount of …
to their families and causes a heavy socioeconomic burden to society. A vast amount of …
Oxidative stress and beta amyloid in Alzheimer's disease. Which comes first: the chicken or the egg?
The pathogenesis of Alzheimer's disease involves β amyloid (Aβ) accumulation known to
induce synaptic dysfunction and neurodegeneration. The brain's vulnerability to oxidative …
induce synaptic dysfunction and neurodegeneration. The brain's vulnerability to oxidative …
Oxidative stress in Alzheimer's disease
Z Chen, C Zhong - Neuroscience bulletin, 2014 - Springer
Oxidative stress plays a significant role in the pathogenesis of Alzheimer's disease (AD), a
devastating disease of the elderly. The brain is more vulnerable than other organs to …
devastating disease of the elderly. The brain is more vulnerable than other organs to …
Oxidative stress and the pathogenesis of Alzheimer′ s disease
Y Zhao, B Zhao - Oxidative medicine and cellular longevity, 2013 - Wiley Online Library
Alzheimer′ s disease (AD) is the most common neurodegenerative disease that causes
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …
Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and Parkinson's disease
G Ganguly, S Chakrabarti, U Chatterjee… - Drug design …, 2017 - Taylor & Francis
Alzheimer's disease and Parkinson's disease are two common neurodegenerative diseases
of the elderly people that have devastating effects in terms of morbidity and mortality. The …
of the elderly people that have devastating effects in terms of morbidity and mortality. The …
PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer's disease
Mitochondrial dysfunction and synaptic damage are early pathological features of the
Alzheimer's disease-affected brain. Memory impairment in Alzheimer's disease is a …
Alzheimer's disease-affected brain. Memory impairment in Alzheimer's disease is a …
Bioinorganic chemistry of Alzheimer's disease
KP Kepp - Chemical reviews, 2012 - ACS Publications
Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
Smoking and increased Alzheimer's disease risk: a review of potential mechanisms
Background Cigarette smoking has been linked with both increased and decreased risk for
Alzheimer's disease (AD). This is relevant for the US military because the prevalence of …
Alzheimer's disease (AD). This is relevant for the US military because the prevalence of …
Molecular mechanisms and genetics of oxidative stress in Alzheimer's disease
F Cioffi, RHI Adam, K Broersen - Journal of Alzheimer's …, 2019 - content.iospress.com
Alzheimer's disease is the most common neurodegenerative disorder that can cause
dementia in elderly over 60 years of age. One of the disease hallmarks is oxidative stress …
dementia in elderly over 60 years of age. One of the disease hallmarks is oxidative stress …
Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease?
Traumatic brain injury (TBI) has devastating acute effects and in many cases seems to
initiate long-term neurodegeneration. Indeed, an epidemiological association between TBI …
initiate long-term neurodegeneration. Indeed, an epidemiological association between TBI …