Integration of GC–MS and LC–MS for untargeted metabolomics profiling
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …
scientific community as it is applied in several researches relating to diseases diagnosis …
Modern analytical techniques in metabolomics analysis
A Zhang, H Sun, P Wang, Y Han, X Wang - Analyst, 2012 - pubs.rsc.org
Metabolomics is the comprehensive assessment of endogenous metabolites and attempts to
systematically identify and quantify metabolites from a biological sample. Small-molecule …
systematically identify and quantify metabolites from a biological sample. Small-molecule …
Mass spectrometry‐based plant metabolomics: Metabolite responses to abiotic stress
TF Jorge, JA Rodrigues, C Caldana… - Mass spectrometry …, 2016 - Wiley Online Library
Metabolomics is one omics approach that can be used to acquire comprehensive
information on the composition of a metabolite pool to provide a functional screen of the …
information on the composition of a metabolite pool to provide a functional screen of the …
New advances in separation science for metabolomics: resolving chemical diversity in a post-genomic era
NL Kuehnbaum, P Britz-McKibbin - Chemical reviews, 2013 - ACS Publications
Metabolomics offers a revolutionary framework for phenoty** individuals at a molecular
level that is needed for new breakthroughs in cell biology and personalized medicine. 1− 3 …
level that is needed for new breakthroughs in cell biology and personalized medicine. 1− 3 …
Untargeted LC/MS-based metabolic phenoty** (metabonomics/metabolomics): The state of the art
Liquid chromatography (LC) hyphenated to mass spectrometry is currently the most widely
used means of determining metabolic phenotypes via both untargeted and targeted …
used means of determining metabolic phenotypes via both untargeted and targeted …
Toward global metabolomics analysis with hydrophilic interaction liquid chromatography–mass spectrometry: improved metabolite identification by retention time …
Metabolomics is an emerging field of postgenomic biology concerned with comprehensive
analysis of small molecules in biological systems. However, difficulties associated with the …
analysis of small molecules in biological systems. However, difficulties associated with the …
Toward 'omic scale metabolite profiling: a dual separation–mass spectrometry approach for coverage of lipid and central carbon metabolism
Although the objective of any 'omic science is broad measurement of its constituents, such
coverage has been challenging in metabolomics because the metabolome is comprised of a …
coverage has been challenging in metabolomics because the metabolome is comprised of a …
Optimized Analytical Procedures for the Untargeted Metabolomic Profiling of Human Urine and Plasma by Combining Hydrophilic Interaction (HILIC) and Reverse …
K Contrepois, L Jiang, M Snyder - Molecular & Cellular Proteomics, 2015 - ASBMB
Profiling of body fluids is crucial for monitoring and discovering metabolic markers of health
and disease and for providing insights into human physiology. Since human urine and …
and disease and for providing insights into human physiology. Since human urine and …
Advances in metabolite identification
DS Wishart - Bioanalysis, 2011 - Taylor & Francis
One of the central challenges to metabolomics is metabolite identification. Regardless of
whether one uses so-called 'targeted'or 'untargeted'metabolomics, eventually all paths lead …
whether one uses so-called 'targeted'or 'untargeted'metabolomics, eventually all paths lead …
An introduction to liquid chromatography–mass spectrometry instrumentation applied in plant metabolomic analyses
JW Allwood, R Goodacre - Phytochemical Analysis: An …, 2010 - Wiley Online Library
Over the past decade the application of non‐targeted high‐throughput metabolomic analysis
within the plant sciences has gained ever increasing interest and has truly established itself …
within the plant sciences has gained ever increasing interest and has truly established itself …