Diagnosis and management of patients with myocardial injury after noncardiac surgery: a scientific statement from the American Heart Association

K Ruetzler, NR Smilowitz, JS Berger, PJ Devereaux… - Circulation, 2021 - ahajournals.org
Myocardial injury after noncardiac surgery is defined by elevated postoperative cardiac
troponin concentrations that exceed the 99th percentile of the upper reference limit of the …

Assessment and treatment of patients with type 2 myocardial infarction and acute nonischemic myocardial injury

AP DeFilippis, AR Chapman, NL Mills, JA De Lemos… - Circulation, 2019 - ahajournals.org
Although coronary thrombus overlying a disrupted atherosclerotic plaque has long been
considered the hallmark and the primary therapeutic target for acute myocardial infarction …

Acute infection and myocardial infarction

DM Musher, MS Abers… - New England Journal of …, 2019 - Mass Medical Soc
Risk of MI after Acute Infection Among patients who are hospitalized for pneumococcal
pneumonia, the incidence of myocardial infarction is 7 to 8%. The true incidence of …

[HTML][HTML] Targeting cytokines, pathogen-associated molecular patterns, and damage-associated molecular patterns in sepsis via blood purification

K Moriyama, O Nishida - International journal of molecular sciences, 2021 - mdpi.com
Sepsis is characterized by a dysregulated immune response to infections that causes life-
threatening organ dysfunction and even death. When infections occur, bacterial cell wall …

Energetic dysfunction in sepsis: a narrative review

S Preau, D Vodovar, B Jung, S Lancel, L Zafrani… - Annals of Intensive …, 2021 - Springer
Background Growing evidence associates organ dysfunction (s) with impaired metabolism
in sepsis. Recent research has increased our understanding of the role of substrate …

Pathophysiology of sepsis-induced myocardial dysfunction

X Lv, H Wang - Military Medical Research, 2016 - Springer
Sepsis-induced myocardial dysfunction is a common complication in septic patients and is
associated with increased mortality. In the clinical setting, it was once believed that …

[HTML][HTML] The role of mitochondria in sepsis-induced cardiomyopathy

G Stanzani, MR Duchen, M Singer - … Acta (BBA)-Molecular Basis of Disease, 2019 - Elsevier
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection. Myocardial dysfunction, often termed sepsis-induced cardiomyopathy …

The worst things in life are free: the role of free heme in sickle cell disease

OT Gbotosho, MG Kapetanaki, GJ Kato - Frontiers in immunology, 2021 - frontiersin.org
Hemolysis is a pathological feature of several diseases of diverse etiology such as
hereditary anemias, malaria, and sepsis. A major complication of hemolysis involves the …

GSDMD mediates LPS-induced septic myocardial dysfunction by regulating ROS-dependent NLRP3 inflammasome activation

S Dai, B Ye, L Zhong, Y Chen, G Hong… - Frontiers in Cell and …, 2021 - frontiersin.org
Myocardial dysfunction is a serious consequence of sepsis and contributes to high mortality.
Currently, the molecular mechanism of myocardial dysfunction induced by sepsis remains …

Emodin alleviates LPS‐induced myocardial injury through inhibition of NLRP3 inflammasome activation

S Dai, B Ye, L Chen, G Hong, G Zhao… - Phytotherapy …, 2021 - Wiley Online Library
Myocardial injury and cardiovascular dysfunction are serious consequences of sepsis and
contribute to high mortality. Currently, the pathogenesis of myocardial injury in sepsis is still …