The aims of this paper are to identify factors that influence the psychosocial difficulties
(PSDs) that persons with epilepsy experience in their everyday life, to describe their onset …

At least one third of patients with active epilepsy suffer from significant impairment of their
emotional well-being. A targeted examination for possible depression (irrespective of any …

Oxcarbazepine (OXC) is an anticonvulsant drug, indicated for the treatment of the
neurological disorder, epilepsy. The objective of the present study was to evaluate the …

The aim of this document is to provide evidence‐based recommendations for the medical
treatment of depression in adults with epilepsy. The working group consisted of members of …

Antiepileptic drugs (AEDs) can have both beneficial and adverse psychotropic effects. They
act on neurotransmitter systems, neuronal ion permeability and other targets, although the …

To produce micro-or nano-sized particles of a solid solute drug, it is necessary to investigate
their solubility behavior in supercritical carbon dioxide (SC-CO 2). In this study, for the first …

A novel substituted oxa/thiadiazolylazetidinonyl/thiazolidinonylcarbazoles (4a-j),(5a-j) and
(6a-j) were synthesized and screened for their antipsychotic and anticonvulsant activities. It …

Lipid-based nanovectors offer effective carriers for brain delivery by improving drug potency
and reducing off-target effects. Emulsomes are nano-triglyceride (TG) carriers formed of lipid …

People with epilepsy (PWE) are more likely to develop depression and both these complex
chronic diseases greatly affect health-related quality of life (QOL). This comorbidity …

Occurring in up to 80% of patients with epilepsy, depression in epilepsy may manifest as (i)
major depressive disorder, meeting Diagnostic and Statistical Manual, 4th edition (DSM-IV) …