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An overview of programmed cell death: apoptosis and pyroptosis—mechanisms, differences, and significance in organism physiology and pathophysiology
S Kowalski, J Karska, Z Łapińska… - Journal of Cellular …, 2023 - Wiley Online Library
Regulated cell death is an essential and heterogeneous process occurring in the life cycle of
organisms, from embryonic development and aging to the regulation of homeostasis and …
organisms, from embryonic development and aging to the regulation of homeostasis and …
Beneath the radar: immune-evasive cell sources for stroke therapy
Stem cell therapy is an emerging treatment paradigm for stroke patients with remaining
neurological deficits. While allogeneic cell transplants overcome the manufacturing …
neurological deficits. While allogeneic cell transplants overcome the manufacturing …
Caspase-9 driven murine model of selective cell apoptosis and efferocytosis
L Batoon, AJ Koh, R Kannan, LK McCauley… - Cell death & …, 2023 - nature.com
Apoptosis and efficient efferocytosis are integral to growth, development, and homeostasis.
The heterogeneity of these mechanisms in different cells across distinct tissues renders it …
The heterogeneity of these mechanisms in different cells across distinct tissues renders it …
Dapagliflozin ameliorates diabetes-induced spermatogenic dysfunction by modulating the adenosine metabolism along the gut microbiota-testis axis
Z **, Y Cao, Q Wen, H Zhang, Z Fang, Q Zhao, Y **… - Scientific Reports, 2024 - nature.com
Male infertility is one of the most common complications of diabetes mellitus (DM).
Dapagliflozin is widely used to manage the type II DM. This study aimed to assess the …
Dapagliflozin is widely used to manage the type II DM. This study aimed to assess the …
Caspase-9 suppresses metastatic behavior of MDA-MB-231 cells in an adaptive organoid model
Abstract Caspase-9, a cysteine-aspartate protease traditionally associated with intrinsic
apoptosis, has recently emerged as having non-apoptotic roles, including influencing cell …
apoptosis, has recently emerged as having non-apoptotic roles, including influencing cell …
The concealed side of caspases: beyond a killer of cells
L Abdelghany, C Sillapachaiyaporn… - Cellular and Molecular …, 2024 - Springer
Since the late 20th century, researchers have known that caspases are a pillar of cell death,
particularly apoptosis. However, recent advances in cell biology have unraveled the multiple …
particularly apoptosis. However, recent advances in cell biology have unraveled the multiple …
Recovery of structural integrity of epithelial monolayer in response to massive apoptosis-induced defects
Apoptosis exists ubiquitously in organisms and plays an essential role in maintaining the
homeostasis of functional tissues. While the signaling pathway of cell apoptosis has been …
homeostasis of functional tissues. While the signaling pathway of cell apoptosis has been …