[HTML][HTML] Exercise, diet and stress as modulators of gut microbiota: Implications for neurodegenerative diseases
The last decade has witnessed an exponentially growing interest in gut microbiota and the
gut-brain axis in health and disease. Accumulating evidence from preclinical and clinical …
gut-brain axis in health and disease. Accumulating evidence from preclinical and clinical …
Environment and gene association with obesity and their impact on neurodegenerative and neurodevelopmental diseases
MT Flores-Dorantes, YE Díaz-López… - Frontiers in …, 2020 - frontiersin.org
Obesity is a multifactorial disease in which environmental conditions and several genes play
an important role in the development of this disease. Obesity is associated with …
an important role in the development of this disease. Obesity is associated with …
Beyond the brain: widespread pathology in Huntington's disease
Huntington's disease (HD) is an inherited neurodegenerative disorder caused by a
polyglutamine stretch in the huntingtin protein. Today, more than 15 years after the genetic …
polyglutamine stretch in the huntingtin protein. Today, more than 15 years after the genetic …
Hypothalamic alterations in neurodegenerative diseases and their relation to abnormal energy metabolism
P Vercruysse, D Vieau, D Blum, Å Petersén… - Frontiers in molecular …, 2018 - frontiersin.org
Neurodegenerative diseases (NDDs) are disorders characterized by progressive
deterioration of brain structure and function. Selective neuronal populations are affected …
deterioration of brain structure and function. Selective neuronal populations are affected …
Weight loss in Huntington disease increases with higher CAG repeat number
NA Aziz, JMM van der Burg, GB Landwehrmeyer… - Neurology, 2008 - AAN Enterprises
Objective: Huntington disease (HD) is a hereditary neurodegenerative disorder caused by
an expanded number of CAG repeats in the huntingtin gene. A hallmark of HD is unintended …
an expanded number of CAG repeats in the huntingtin gene. A hallmark of HD is unintended …
Energy deficit in Huntington disease: why it matters
Huntington disease (HD) is an autosomal dominant neurodegenerative disease with
complete penetrance. Although the understanding of the cellular mechanisms that drive …
complete penetrance. Although the understanding of the cellular mechanisms that drive …
Sha** the role of mitochondria in the pathogenesis of Huntington's disease
V Costa, L Scorrano - The EMBO journal, 2012 - embopress.org
Intense research on the pathogenesis of Huntington's disease (HD), a genetic
neurodegenerative disease caused by a polyglutamine expansion in the Huntingtin (Htt) …
neurodegenerative disease caused by a polyglutamine expansion in the Huntingtin (Htt) …
Body weight is a robust predictor of clinical progression in Huntington disease
JMM van der Burg, SL Gardiner, AC Ludolph… - Annals of …, 2017 - Wiley Online Library
Unintended weight loss is a hallmark of Huntington disease (HD), but it is unknown to what
extent weight loss impacts the rate of disease progression. Therefore, using longitudinal …
extent weight loss impacts the rate of disease progression. Therefore, using longitudinal …
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons
Huntington's disease (HD) is caused by an expanded CAG repeat in the huntingtin gene,
yielding a Huntingtin protein with an expanded polyglutamine tract. While experiments with …
yielding a Huntingtin protein with an expanded polyglutamine tract. While experiments with …
Huntington's disease: the current state of research with peripheral tissues
J Sassone, C Colciago, G Cislaghi, V Silani… - Experimental …, 2009 - Elsevier
Huntington's disease (HD) is a genetically dominant condition caused by expanded CAG
repeats. These repeats code for a glutamine tract in the HD gene product huntingtin (htt) …
repeats. These repeats code for a glutamine tract in the HD gene product huntingtin (htt) …