Signaling pathways and targeted therapy for rosacea

F Yang, L Wang, D Song, L Zhang, X Wang… - Frontiers in …, 2024 - frontiersin.org
Rosacea is a chronic skin inflammatory disease with a global prevalence ranging from 1% to
20%. It is characterized by facial erythema, telangiectasia, papules, pustules, and ocular …

Extraction, detection, bioactivity, and product development of luteolin: A review

F Ren, Y Li, H Luo, S Gao, S Jiang, J Yang, C Rao… - Heliyon, 2024 - cell.com
Luteolin is a kind of natural flavonoid, widely existing in a variety of plants, has been
revealed to have a wide range of biological activities. In recent years, the research results of …

[HTML][HTML] Ferulic Acid Alleviates Radiation-Induced Immune Damage by Acting on JAK/STAT Signaling Pathway

M Huang, A Ye, H Zhang, J Chen, T Yang, X Wei… - Pharmaceuticals, 2024 - mdpi.com
The disruption of hematopoietic and immune functions is a significant consequence of the
long-term effects of radiation exposure. This study investigated the potential mechanisms by …

Correction: The JAK-STAT pathway: from structural biology to cytokine engineering

Y Lv, J Qi, JJ Babon, L Cao, G Fan, J Lang… - … and Targeted Therapy, 2024 - nature.com
After online publication of the Article, 1 the authors received feedback from a reader that an
inadvertent error was found on earlier understanding on the organizing principle of common …

The Effect of Cancer Cell-Derived Exosomal Proteins on Macrophage Polarization: An In-depth Review

K Wadhonkar, S Das, R Subramanian, MH Sk… - Experimental Cell …, 2024 - Elsevier
Background: Cancer is characterized by unregulated cell proliferation, enabling it to invade
and spread to different organs and tissues in the body. Cancer progression is intricately …

[HTML][HTML] Mycophenolate Mofetil, an Inhibitor of Inosine Monophosphate Dehydrogenase, and Tofacitinib, a Janus Kinase Inhibitor, Attenuate Airway Inflammation and …

B Kravčenia, T Maślanka - Molecules, 2024 - mdpi.com
Treatment-resistant asthma remains an unresolved clinical problem and a challenge for
current medical science. Consequently, there is a growing and urgent need to develop novel …

Pharmaceutical aspects of JAK inhibitors: a comparative review

S **esh, R Radhakrishnan - Inflammopharmacology, 2024 - Springer
Janus kinase inhibitors (JAKIs) are a new class of drugs used in the treatment of a
heterogeneous group of diseases, mainly inflammatory and autoimmune diseases. Janus …

Hypoxia-inducible Factor-1α Pathway in Cerebral Ischemia: From Molecular Mechanisms to Therapeutic Targets

V Sharma, TG Singh - CNS & Neurological Disorders-Drug …, 2025 - benthamdirect.com
Introduction Ischemic injury to the brain can result in a variety of life-threatening conditions,
mortality, or varying degrees of disability. Hypoxia-inducible factor 1α (HIF 1α), an oxygen …

Tumor microbiome: roles in tumor initiation, progression, and therapy

S Zhang, J Huang, Z Jiang, H Tong, X Ma, Y Liu - Molecular Biomedicine, 2025 - Springer
Over the past few years, the tumor microbiome is increasingly recognized for its multifaceted
involvement in cancer initiation, progression, and metastasis. With the application of 16S …

In silico-based investigation of the molecular mechanism of Artocarpus communis seed hexane fraction against metabolic syndrome

A Elbasyouni, D Prabhu, EO Akindoyin… - Journal of Molecular …, 2025 - Springer
Methods Solvent-based extraction was performed in this study to extract the phytochemicals
in Artocarpus communis seed powder. The hexane fraction was subjected to GCMS analysis …