Pragmatic trials

I Ford, J Norrie - New England journal of medicine, 2016 - Mass Medical Soc
In pragmatic trials, participants are broadly representative of people who will receive a
treatment or diagnostic strategy, and the outcomes affect day-to-day care. The authors …

[HTML][HTML] Applications of synthetic polymers in clinical medicine

MF Maitz - Biosurface and Biotribology, 2015 - Elsevier
Multiple biological, synthetic and hybrid polymers are used for multiple medical applications.
A wide range of different polymers is available, and they have further the advantage to be …

A review of the recent advances in antimicrobial coatings for urinary catheters

P Singha, J Locklin, H Handa - Acta biomaterialia, 2017 - Elsevier
More than 75% of hospital-acquired or nosocomial urinary tract infections are initiated by
urinary catheters, which are used during the treatment of 15–25% of hospitalized patients …

Biofilm-related infections: bridging the gap between clinical management and fundamental aspects of recalcitrance toward antibiotics

D Lebeaux, JM Ghigo, C Beloin - Microbiology and Molecular …, 2014 - journals.asm.org
Surface-associated microbial communities, called biofilms, are present in all environments.
Although biofilms play an important positive role in a variety of ecosystems, they also have …

Healthcare-associated infections, medical devices and biofilms: risk, tolerance and control

SL Percival, L Suleman, C Vuotto… - Journal of medical …, 2015 - microbiologyresearch.org
Biofilms are of great importance in infection control and healthcare-associated infections
owing to their inherent tolerance and 'resistance'to antimicrobial therapies. Biofilms have …

[HTML][HTML] ESCMID guideline for the diagnosis and treatment of biofilm infections 2014

N Høiby, T Bjarnsholt, C Moser, GL Bassi… - Clinical microbiology …, 2015 - Elsevier
Biofilms cause chronic infections in tissues or by develo** on the surfaces of medical
devices. Biofilm infections persist despite both antibiotic therapy and the innate and adaptive …

Pathophysiology, treatment, and prevention of catheter-associated urinary tract infection

A Flores-Mireles, TN Hreha… - Topics in spinal cord …, 2019 - meridian.allenpress.com
Urinary tract infections (UTIs) are among the most common microbial infections in humans
and represent a substantial burden on the health care system. UTIs can be uncomplicated …

A review of the biomaterials technologies for infection-resistant surfaces

D Campoccia, L Montanaro, CR Arciola - Biomaterials, 2013 - Elsevier
Anti-infective biomaterials need to be tailored according to the specific clinical application.
All their properties have to be tuned to achieve the best anti-infective performance together …

Reporting of multi-arm parallel-group randomized trials: extension of the CONSORT 2010 statement

E Juszczak, DG Altman, S Hopewell, K Schulz - Jama, 2019 - jamanetwork.com
Importance The quality of reporting of randomized clinical trials is suboptimal. In an era in
which the need for greater research transparency is paramount, inadequate reporting …

Strategies to prevent catheter-associated urinary tract infections in acute care hospitals: 2014 update

E Lo, LE Nicolle, SE Coffin, C Gould… - Infection Control & …, 2014 - cambridge.org
Previously published guidelines are available that provide comprehensive
recommendations for detecting and preventing healthcare-associated infections (HAIs). The …