From Pavlov to PTSD: the extinction of conditioned fear in rodents, humans, and anxiety disorders
MB VanElzakker, MK Dahlgren, FC Davis… - Neurobiology of learning …, 2014 - Elsevier
Abstract Nearly 100 years ago, Ivan Pavlov demonstrated that dogs could learn to use a
neutral cue to predict a biologically relevant event: after repeated predictive pairings …
neutral cue to predict a biologically relevant event: after repeated predictive pairings …
The neurocircuitry of fear, stress, and anxiety disorders
Anxiety disorders are a significant problem in the community, and recent neuroimaging
research has focused on determining the brain circuits that underlie them. Research on the …
research has focused on determining the brain circuits that underlie them. Research on the …
Neural signatures of human fear conditioning: an updated and extended meta-analysis of fMRI studies
Classical Pavlovian fear conditioning remains the most widely employed experimental
model of fear and anxiety, and continues to inform contemporary pathophysiological …
model of fear and anxiety, and continues to inform contemporary pathophysiological …
Fear extinction relies on ventral hippocampal safety codes shaped by the amygdala
Extinction memory retrieval is influenced by spatial contextual information that determines
responding to conditioned stimuli (CS). However, it is poorly understood whether contextual …
responding to conditioned stimuli (CS). However, it is poorly understood whether contextual …
Implicit cognition and addiction: a tool for explaining paradoxical behavior
Research on implicit cognition and addiction has expanded greatly during the past decade.
This research area provides new ways to understand why people engage in behaviors that …
This research area provides new ways to understand why people engage in behaviors that …
PTSD-related neuroimaging abnormalities in brain function, structure, and biochemistry
Although approximately 90% of the US population will experience a traumatic event within
their lifetime, only a fraction of those traumatized individuals will develop posttraumatic …
their lifetime, only a fraction of those traumatized individuals will develop posttraumatic …
How the neurocircuitry and genetics of fear inhibition may inform our understanding of PTSD
Exposure to traumatic events that produce extreme fear and horror is all too common in both
military and civilian populations, but not all individuals develop posttraumatic stress disorder …
military and civilian populations, but not all individuals develop posttraumatic stress disorder …
A meta-analysis of instructed fear studies: implications for conscious appraisal of threat
ML Mechias, A Etkin, R Kalisch - Neuroimage, 2010 - Elsevier
In classical Pavlovian fear conditioning, a neutral stimulus (conditioned stimulus, CS) comes
to be evaluated as threatening due to its association with an aversive stimulus …
to be evaluated as threatening due to its association with an aversive stimulus …
Development of anxiety: The role of threat appraisal and fear learning
Anxious individuals exhibit threat biases at multiple levels of information processing. From a
developmental perspective, abnormal safety learning in childhood may establish threat …
developmental perspective, abnormal safety learning in childhood may establish threat …
Learning: From association to cognition
DR Shanks - Annual review of psychology, 2010 - annualreviews.org
Since the very earliest experimental investigations of learning, tension has existed between
association-based and cognitive theories. Associationism accounts for the phenomena of …
association-based and cognitive theories. Associationism accounts for the phenomena of …