[HTML][HTML] Endometriosis-associated infertility: From pathophysiology to tailored treatment

G Bonavina, HS Taylor - Frontiers in endocrinology, 2022 - frontiersin.org
Despite the clinically recognized association between endometriosis and infertility, the
mechanisms implicated in endometriosis-associated infertility are not fully understood …

Pathophysiology, diagnosis, and management of endometriosis

AW Horne, SA Missmer - bmj, 2022 - bmj.com
Endometriosis affects approximately 190 million women and people assigned female at birth
worldwide. It is a chronic, inflammatory, gynecologic disease marked by the presence of …

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

N Rahmioglu, S Mortlock, M Ghiasi, PL Møller… - Nature …, 2023 - nature.com
Endometriosis is a common condition associated with debilitating pelvic pain and infertility.
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …

Endometriosis: Etiology, pathobiology, and therapeutic prospects

PTK Saunders, AW Horne - Cell, 2021 - cell.com
Endometriosis is a common condition associated with infertility that causes chronic pain in
many, but not all, women. It is defined by the presence of endometrial-like tissue outside the …

The pathogenesis of endometriosis: molecular and cell biology insights

AS Laganà, S Garzon, M Götte, P Viganò… - International journal of …, 2019 - mdpi.com
The etiopathogenesis of endometriosis is a multifactorial process resulting in a
heterogeneous disease. Considering that endometriosis etiology and pathogenesis are still …

Obesity and risk of female reproductive conditions: A Mendelian randomisation study

SS Venkatesh, T Ferreira, S Benonisdottir… - PLoS …, 2022 - journals.plos.org
Background Obesity is observationally associated with altered risk of many female
reproductive conditions. These include polycystic ovary syndrome (PCOS), abnormal uterine …

The origin and pathogenesis of endometriosis

Y Wang, K Nicholes, IM Shih - Annual Review of Pathology …, 2020 - annualreviews.org
Recent molecular genetic findings on endometriosis and normal endometrium suggest a
modified model in which circulating epithelial progenitor or stem cells intended to …

Discovery of common and rare genetic risk variants for colorectal cancer

JR Huyghe, SA Bien, TA Harrison, HM Kang, S Chen… - Nature …, 2019 - nature.com
To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-
genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence …

Endometriosis: advances and controversies in classification, pathogenesis, diagnosis, and treatment

E Rolla - F1000Research, 2019 - pmc.ncbi.nlm.nih.gov
Endometriosis is an enigmatic disease that could start at birth. Its pathogenesis is supported
by different theories. Accumulating facts relate it to a multigenic disorder. In this review of …

The association between endometriosis and autoimmune diseases: a systematic review and meta-analysis

N Shigesi, M Kvaskoff, S Kirtley, Q Feng… - Human reproduction …, 2019 - academic.oup.com
BACKGROUND Endometriosis is a chronic gynaecological disorder that affects 2–10% of
women of reproductive age. The aetiology of endometriosis is largely under-explored, yet …