Birth defects, also known as congenital disorders, are a significant health issue impacting at
least five million births annually worldwide. For policymakers to mount a relevant healthcare …

Study design HAALSI is a population-based community observational study with
longitudinal follow-up at 3-year intervals. Embedded in the study are several randomized …

Human gut microbiome research focuses on populations living in high-income countries and
to a lesser extent, non-urban agriculturalist and hunter-gatherer societies. The scarcity of …

Introduction: South Africa has an appreciable burden of both communicable and non-
communicable diseases as well as high maternal, neonatal, and child morbidity. In recent …

Objectives To explore the opportunities and challenges within the health system to facilitate
the achievement of universal health coverage (UHC) for people with stroke (PWS) in South …

Background Comparisons of traditional hunter-gatherers and pre-agricultural communities
in Africa with urban and suburban Western North American and European cohorts have …

We assessed the health risks of fine particulate matter (PM2. 5) ambient air pollution and its
trace elemental components in a rural South African community. Air pollution is the largest …

Background Understanding the effects of socioeconomic disparities in health outcomes is
important to implement specific preventive actions. We assessed socioeconomic disparities …

Introduction: Despite rapid population aging, there are currently limited data on the
incidence of aging-related cognitive impairment in sub-Saharan Africa. We aimed to …

Introduction Community health worker teams are potential game-changers in ensuring
access to care in vulnerable communities. Who are they? What do they actually do? Can …