Predicting protein structural classes for low-similarity sequences by evaluating different features

XJ Zhu, CQ Feng, HY Lai, W Chen, L Hao - Knowledge-Based Systems, 2019 - Elsevier
Protein structural class could provide important clues for understanding protein fold,
evolution and function. However, it is still a challenging problem to accurately predict protein …

Predicting flexible length linear B-cell epitopes

ELM Yasser, D Dobbs… - Computational systems …, 2008 - pmc.ncbi.nlm.nih.gov
Identifying B-cell epitopes play an important role in vaccine design, immunodiagnostic tests,
and antibody production. Therefore, computational tools for reliably predicting B-cell …

Integrating machine learning to advance epitope map**

S Grewal, N Hegde, SK Yanow - Frontiers in Immunology, 2024 - frontiersin.org
Identifying epitopes, or the segments of a protein that bind to antibodies, is critical for the
development of a variety of immunotherapeutics and diagnostics. In vaccine design, the …

A feature extraction technique using bi-gram probabilities of position specific scoring matrix for protein fold recognition

A Sharma, J Lyons, A Dehzangi, KK Paliwal - Journal of theoretical biology, 2013 - Elsevier
Discovering a three dimensional structure of a protein is a challenging task in biological
science. Classifying a protein into one of its folds is an intermediate step for deciphering the …

A Bayesian network model for predicting post-stroke outcomes with available risk factors

E Park, H Chang, HS Nam - Frontiers in neurology, 2018 - frontiersin.org
Bayesian network is an increasingly popular method in modeling uncertain and complex
problems, because its interpretability is often more useful than plain prediction. To satisfy the …

[HTML][HTML] Predicting subcellular localization of multi-label proteins by incorporating the sequence features into Chou's PseAAC

F Javed, M Hayat - Genomics, 2019 - Elsevier
The emergence of numerous genome projects has made the experimental classification of
the protein localization almost impossible due to the exponential increase in the number of …

[КНИГА][B] Pharmacoeconomics: from theory to practice

RJG Arnold - 2016 - taylorfrancis.com
The pharmaceutical industry is almost boundless in its ability to supply new drug therapies,
but how does one decide which are the best medicines to use within restricted budgets …

Improved naive Bayesian modeling of numerical data for absorption, distribution, metabolism and excretion (ADME) property prediction

AE Klon, JF Lowrie, DJ Diller - Journal of chemical information and …, 2006 - ACS Publications
We have implemented a naïve Bayesian classifier which models continuous numerical data
using a Gaussian distribution. Several cases of interest in the area of absorption …

A tri-gram based feature extraction technique using linear probabilities of position specific scoring matrix for protein fold recognition

KK Paliwal, A Sharma, J Lyons… - IEEE transactions on …, 2014 - ieeexplore.ieee.org
In biological sciences, the deciphering of a three dimensional structure of a protein
sequence is considered to be an important and challenging task. The identification of protein …

The use of automated SNOMED CT clinical coding in clinical decision support systems for preventive care

B Al-Hablani - Perspectives in health information management, 2017 - pmc.ncbi.nlm.nih.gov
Objective The objective of this study is to discuss and analyze the use of automated
SNOMED CT clinical coding in clinical decision support systems (CDSSs) for preventive …