Hepatocellular carcinoma (HCC) is a common malignancy and one of the leading causes of
cancer-related death. The biological process of HCC is complex, with multiple factors …

Cyclic adenosine monophosphate (cAMP) is the first discovered second messenger, which
plays pivotal roles in cell signaling, and regulates many physiological and pathological …

Despite advances in the treatment of cancers through surgical procedures and new
pharmaceuticals, the treatment of hepatocellular carcinoma (HCC) remains challenging as …

Chronic infection with viral hepatitis affects half a billion individuals worldwide and can lead
to cirrhosis, cancer, and liver failure. Liver cancer is the third leading cause of cancer …

Abstract The Hippo–YAP (Yes-associated protein) pathway is an evolutionarily and
functionally conserved regulator of organ size and growth with crucial roles in cell …

Hepatitis B virus (HBV) infection is a major driver of hepatocarcinogenesis. Ferroptosis is a
type of iron-mediated cell death that can suppress liver transformation. Previous studies …

The Hippo signalling pathway is an emerging growth control and tumour suppressor
pathway that regulates cell proliferation and stem cell functions. Defects in Hippo signalling …

The Hippo signaling pathway, also known as the Salvador− Warts− Hippo pathway, is a
regulator of organ size. The pathway takes its name from the Drosophila protein kinase …

Some types of circular RNA (circRNA) are aberrantly expressed in human diseases
including hepatocellular carcinoma (HCC). However, its regulation mechanism and …

The Hippo pathway is a signalling cascade conserved from Drosophila melanogaster to
mammals. The mammalian core kinase components comprise MST1 and MST2, SAV1 …