Glaucoma is the leading cause of irreversible blindness globally. The disease causes vision
loss due to neurodegeneration of the retinal ganglion cell (RGC) projection to the brain …

Dendrite pathology and synaptic loss result in neural circuit dysfunction, a common feature
of neurodegenerative diseases. There is a lack of strategies that target dendritic and …

The retina is the sensory tissue responsible for the first stages of visual processing, with a
conserved anatomy and functional architecture among vertebrates. To date, retinal eye …

The vasculature of the central nervous system is a 3D lattice composed of laminar vascular
beds interconnected by penetrating vessels. The mechanisms controlling 3D lattice network …

In an attempt to repair injured central nervous system (CNS) nerves/tracts, immune cells are
recruited into the injury site, but endogenous response in adult mammals is insufficient for …

Retinal diseases often lead to degeneration of specific retinal cell types with currently limited
therapeutic options to replace the lost neurons. Previous studies have reported that …

The Myc family of proto-oncogenes is a key node for the signal transduction of external pro-
proliferative signals to the cellular processes required for development, tissue homoeostasis …

While preclinical efforts continue in several laboratories, an increasing number of start-up
and large pharmaceutical companies are working on develo** gene therapeutics for …

Retinal ganglion cells (RGCs) are the brain's gateway for vision, and their degeneration
underlies several blinding diseases. RGCs interact with other neuronal cell types, microglia …

Introduction: Advances in machine vision and mobile electronics will be accelerated by the
creation of sophisticated optoelectronic vision sensors that allow for sophisticated picture …