As an ancient infectious disease, tuberculosis (TB) is still the leading cause of death from a
single infectious agent worldwide. Latent TB infection (LTBI) has been recognized as the …

Practitioners of ancient societies from the time of Hippocrates and earlier recognized and
treated the signs of inflammation, heat, redness, swelling, and pain with agents that block or …

Tuberculosis remains the leading cause of death from an infectious disease worldwide.
Early and accurate diagnosis and detection of drug-sensitive and drug-resistant tuberculosis …

Complex and dynamic networks of molecules are involved in human diseases. High-
throughput technologies enable omics studies interrogating thousands to millions of makers …

The acute inflammatory response is host-protective to contain foreign invaders. Many of
today's pharmacopeia that block pro-inflammatory chemical mediators can cause serious …

Metabolomics is an emerging approach in a systems biology field. Due to continuous
development in advanced analytical techniques and in bioinformatics, metabolomics has …

Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …

Essential fatty acids can serve as important regulators of inflammation. A new window into
mechanisms for the resolution of inflammation was opened with the identification and …

Endogenous mechanisms that orchestrate resolution of acute inflammation are essential in
host defense and the return to homeostasis. Resolvin (Rv) D2 is a potent immunoresolvent …

Metabolomics has emerged as an invaluable tool that can be used along with genomics,
transcriptomics and proteomics to understand host–pathogen interactions at small-molecule …