Zebrafish models for studying cognitive enhancers
Cognitive decline is commonly seen both in normal aging and in neurodegenerative and
neuropsychiatric diseases. Various experimental animal models represent a valuable tool to …
neuropsychiatric diseases. Various experimental animal models represent a valuable tool to …
Neurotransmitter Metabolism in Arsenic Exposure-Induced Cognitive Impairment: Emerging Insights and Predictive Implications
W Wang, B Sun, D Luo, X Chen, M Yao… - … Science & Technology, 2024 - ACS Publications
Scholars have long been interested in the association between arsenic (As) exposure and
neurological disorders; however, existing systematic epidemiological investigations are …
neurological disorders; however, existing systematic epidemiological investigations are …
Zinc attenuates arsenic overdose-induced brain damage via PERK/ATF6 and TLR/MyD88/NF-κB pathways
W Wang, Y Zhang, X Geng, H Li, X Wang… - … and Physiology Part C …, 2024 - Elsevier
Exposure to arsenic (As), a widespread non-metallic toxicant in nature, often results in
neurotoxicity, although the exact mechanism is unknown. Zinc (Zn) is a powerful nutrient …
neurotoxicity, although the exact mechanism is unknown. Zinc (Zn) is a powerful nutrient …
Bioaccumulation and toxicological effects of dietborne arsenic exposure on the apple snail (Pomacea canaliculata)
X Bi, Y Liu, Y Wang, D Li, H Li, R Qiu, G Chen - Journal of Hazardous …, 2024 - Elsevier
An eight-compartment physiologically based pharmacokinetic (PBPK) model was used to
simulate the bioaccumulation and distribution of arsenic (As) within the apple snail …
simulate the bioaccumulation and distribution of arsenic (As) within the apple snail …
Fisetin attenuates arsenic and fluoride subacute co-exposure induced neurotoxicity via regulating TNF-α mediated activation of NLRP3 inflammasome
Groundwater is considered safe, however, the occurrence of contaminants like arsenic and
fluoride has raised a major healthcare concern. Clinical studies suggested that arsenic and …
fluoride has raised a major healthcare concern. Clinical studies suggested that arsenic and …
Oral arsenite exposure induces inflammation and apoptosis in pulmonary tissue: acute and chronic evaluation in young and adult mice
Inorganic arsenic is a well-known environmental toxicant, and exposure to this metalloid is
strongly linked with severe and extensive toxic effects in various organs including the lungs …
strongly linked with severe and extensive toxic effects in various organs including the lungs …
Arsenic bioaccumulation and biotransformation in the marine copepod Tigriopus japonicus under chronic dietborne and waterborne exposure
T Liu, H Lin, L Zhang - Journal of Hazardous Materials, 2024 - Elsevier
Arsenic (As) can be transferred along the food chain, while little is known about the toxic
effects of dietborne As on marine copepods. In this study, we investigated the short-term and …
effects of dietborne As on marine copepods. In this study, we investigated the short-term and …
A Comprehensive Review on Molecular Mechanism Involved in Arsenic Trioxide Mediated Cerebral Neurodegenerative and Infectious Diseases
Arsenic is an environmental toxicant and its toxicity is a global health problem affecting
millions of people. Arsenic exposure occurs from natural geological sources leaching into …
millions of people. Arsenic exposure occurs from natural geological sources leaching into …
Dietary copper for fish: Homeostasis, nutritional functions, toxicity, and affecting factors
L Wang, H Wang, C Gao, C Wang, Y Yan, F Zhou - Aquaculture, 2024 - Elsevier
Copper (Cu) is an essential element for various vital biological processes, but a
comprehensive systematic review focusing on Cu metabolism, deposition, nutritional …
comprehensive systematic review focusing on Cu metabolism, deposition, nutritional …
The dopamine transporter inhibition using GBR 12909 as a novel pharmacological tool to assess bipolar disorder-like neurobehavioral phenotypes in zebrafish
J Canzian, JV Borba, CM Resmim… - Behavioural Brain …, 2024 - Elsevier
Dopamine (DA) is a neurotransmitter that plays an important role in brain physiology.
Changes in DA-mediated signaling has been implicated with the pathophysiology of various …
Changes in DA-mediated signaling has been implicated with the pathophysiology of various …