Thrombocytopenia in malaria: who cares?

MVG Lacerda, MPG Mourão, HCC Coelho… - Memorias do Instituto …, 2011 - SciELO Brasil
Despite not being a criterion for severe malaria, thrombocytopenia is one of the most
common complications of both Plasmodium vivax and Plasmodium falciparum malaria. In a …

The immunological balance between host and parasite in malaria

K Deroost, TT Pham, G Opdenakker… - FEMS microbiology …, 2016 - academic.oup.com
Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

Effect of malarial infection on haematological parameters in population near Thailand-Myanmar border

M Kotepui, B Phunphuech, N Phiwklam, C Chupeerach… - Malaria journal, 2014 - Springer
Background Malaria is a major mosquito-borne public health problem in Thailand with
varied haematological consequences. The study sought to elucidate the haematological …

Impact of Plasmodium falciparum infection on haematological parameters in children living in Western Kenya

RN Maina, D Walsh, C Gaddy, G Hongo, J Waitumbi… - Malaria journal, 2010 - Springer
Background Malaria is the commonest cause of childhood morbidity in Western Kenya with
varied heamatological consequences. The t study sought to elucidate the haemotological …

Effects of malaria parasite density on blood cell parameters

M Kotepui, D Piwkham, B PhunPhuech, N Phiwklam… - PloS one, 2015 - journals.plos.org
Changes in blood cell parameters are already a well-known feature of malarial infections. To
add to this information, the objective of this study was to investigate the varying effects that …

Neutrophil extracellular traps drive inflammatory pathogenesis in malaria

SL Knackstedt, A Georgiadou, F Apel… - Science …, 2019 - science.org
Neutrophils are essential innate immune cells that extrude chromatin in the form of
neutrophil extracellular traps (NETs) when they die. This form of cell death has potent …

Platelets kill intraerythrocytic malarial parasites and mediate survival to infection

BJ McMorran, VM Marshall, C De Graaf, KE Drysdale… - Science, 2009 - science.org
Platelets play a critical role in the pathogenesis of malarial infections by encouraging the
sequestration of infected red blood cells within the cerebral vasculature. But platelets also …

Malarial anemia: of mice and men

AA Lamikanra, D Brown, A Potocnik… - Blood, The Journal …, 2007 - ashpublications.org
Severe malaria is manifest by a variety of clinical syndromes dependent on properties of
both the host and the parasite. In young infants, severe malarial anemia (SMA) is the most …

Platelet Factor 4 and Duffy Antigen Required for Platelet Killing of Plasmodium falciparum

BJ McMorran, L Wieczorski, KE Drysdale, JA Chan… - Science, 2012 - science.org
Platelets restrict the growth of intraerythrocytic malaria parasites by binding to parasitized
cells and killing the parasite within. Here, we show that the platelet molecule platelet factor 4 …

White blood cell counts and malaria

FE McKenzie, WA Prudhomme, AJ Magill… - The Journal of …, 2005 - academic.oup.com
White blood cells (WBCs) were counted in 4697 individuals who presented to outpatient
malaria clinics in Maesod, Tak Province, Thailand, and Iquitos, Peru, between 28 May and …