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Design, synthesis, characterization, and anti-tubercular activity of novel ethyl-3-benzoyl-6, 8-difluoroindolizine-1-carboxylate analogues: molecular target identification …
P Mundhe, S Kidwai, SM Saini, HR Singh… - Journal of Molecular …, 2023 - Elsevier
A series of novel Ethyl-3-benzoyl-6, 8-difluoroindolizine-1-carboxylate analogues (4a-r)
were synthesized by reacting 3, 5-difluoropyridine, with phenacyl bromide to get quaternary …
were synthesized by reacting 3, 5-difluoropyridine, with phenacyl bromide to get quaternary …
Tandem-Michael-cyclization cascade to make pyridines: Use of electron-deficient acetylenes for the synthesis of indolizines in aqueous media
K Lakshmikanth, SM Saini, ST Dorai… - Tetrahedron, 2023 - Elsevier
A mild, greener approach via tandem-Michael-cyclization cascade reaction towards the
construction of a group of di-and tri-differently substituted indolizine with a broad scope of …
construction of a group of di-and tri-differently substituted indolizine with a broad scope of …
Anti-tubercular activity and molecular docking studies of indolizine derivatives targeting mycobacterial InhA enzyme
Abstract A series of 1, 2, 3-trisubstituted indolizines (2a–2f, 3a–3d, and 4a–4c) were
screened for in vitro whole-cell anti-tubercular activity against the susceptible H37Rv and …
screened for in vitro whole-cell anti-tubercular activity against the susceptible H37Rv and …
[HTML][HTML] Investigation of antifungal properties of synthetic dimethyl-4-bromo-1-(substituted benzoyl) pyrrolo [1, 2-a] quinoline-2, 3-dicarboxylates analogues: Molecular …
Candida albicans, an opportunistic fungal pathogen, frequently colonizes immune-
compromised patients and causes mild to severe systemic reactions. Only few antifungal …
compromised patients and causes mild to severe systemic reactions. Only few antifungal …
Microwave-assisted improved regioselective synthesis of 3-benzoyl indolizine derivatives
An efficient and facile method is developed to synthesize 3-benzoyl indolizines by two-
component reaction under microwave irradiation. A wide range of substrates could be …
component reaction under microwave irradiation. A wide range of substrates could be …
Bridging the Chemical Profile and Biological Activities of a New Variety of Agastache foeniculum (Pursh) Kuntze Extracts and Essential Oil
This study investigated the phytochemical content of alcoholic extracts and essential oil of a
new variety of medicinal plants, Agastache foeniculum (Pursh), which Kuntze adapted for …
new variety of medicinal plants, Agastache foeniculum (Pursh), which Kuntze adapted for …
Computational evaluation of ADMET properties and bioactive score of compounds from Encephalartos ferox
Background: Plant based products are recognised as sources of drugs for treatment of
diseases. Objective: The study aimed at predicting the physicochemical, pharmacokinetics …
diseases. Objective: The study aimed at predicting the physicochemical, pharmacokinetics …
Design, synthesis and characterization of ethyl 3‐benzoyl‐7‐morpholinoindolizine‐1‐carboxylate as anti‐tubercular agents: In silico screening for possible target …
P Tiwari, GS Mangubhai, S Kidwai… - Chemical Biology & …, 2024 - Wiley Online Library
A thorough search for the development of innovative drugs to treat tuberculosis, especially
considering the urgent need to address develo** drug resistance, we report here a …
considering the urgent need to address develo** drug resistance, we report here a …
One-pot construction of novel trifluoromethyl dihydro-imidazo [1, 2-a] pyridine: A greener approach
A one-pot three-component method for the synthesis of 3-substituted 2-trifluoromethyl-2, 3-
dihydroimidazo [1, 2-a] pyridin-3-yl analogues from 2-aminopyridine, substituted phenacyl …
dihydroimidazo [1, 2-a] pyridin-3-yl analogues from 2-aminopyridine, substituted phenacyl …
Design, synthesis and characterization of novel 2-(2, 3-dichlorophenyl)-5-aryl-1, 3, 4-oxadiazole derivatives for their anti-tubercular activity against Mycobacterium …
R Ningegowda, S Chandrashekharappa… - Chemical Data …, 2020 - Elsevier
Tuberculosis (TB) remains the leading cause of death from an infectious disease globally.
The chemotherapy of TB is complicated by the protracted treatment regimens, development …
The chemotherapy of TB is complicated by the protracted treatment regimens, development …