Lipid rafts are membrane microdomains that are enriched in cholesterol and
glycosphingolipids. They have been implicated in processes as diverse as signal …

Covering: up to 2012 Steroids, a widespread class of natural organic compounds occurring
in animals, plants and fungi, have shown great therapeutic value for a broad array of …

Incomplete understanding of how hepatosteatosis transitions to fibrotic non-alcoholic
steatohepatitis (NASH) has limited therapeutic options. Two molecules that are elevated in …

Lipid rafts/caveolae are membrane platforms for signaling molecules that regulate various
cellular functions, including cell survival. To better understand the role of rafts in tumor …

Lipid rafts are plasma membrane microdomains enriched in cholesterol and sphingolipids
that are involved in the lateral compartmentalization of molecules at the cell surface …

Oxysterols are a class of endogenous signaling molecules that can activate the Hedgehog
pathway, which has critical roles in development, regeneration and cancer. However, it has …

Lipid rafts are microdomains of the plasma membrane enriched in cholesterol and
sphingolipids, and play an important role in the initiation of many pharmacological agent …

Macrophages in advanced atherosclerotic lesions accumulate large amounts of unesterified,
or" free," cholesterol (FC). FC accumulation induces macrophage apoptosis, which likely …

• Introduction• Raft‐dependent endocytosis encompasses various pathways• Cav1 and the
regulation of raft‐dependent endocytosis• Signaling and raft‐dependent endocytosis• …

Growth factor receptors have been shown to be localized to lipid rafts and caveolae.
Consistent with a role for these cholesterol-enriched membrane domains in growth factor …