Contrastive learning of T cell receptor representations
Computational prediction of the interaction of T cell receptors (TCRs) and their ligands is a
grand challenge in immunology. Despite advances in high-throughput assays, specificity …
grand challenge in immunology. Despite advances in high-throughput assays, specificity …
A Large Language Model Guides the Affinity Maturation of Variant Antibodies Generated by Combinatorial Optimization
FB Ashraf, Z Zhang, K Paco, MP Mendivil, JA Lay… - bioRxiv, 2024 - biorxiv.org
Abstract Machine learning-based antibody design and optimization by computational affinity
maturation is emerging as a promising approach to combating infectious diseases. This has …
maturation is emerging as a promising approach to combating infectious diseases. This has …