[HTML][HTML] Autophagy in inflammation, infection, and immunometabolism
V Deretic - Immunity, 2021 - cell.com
Autophagy is a quality-control, metabolic, and innate immunity process. Normative
autophagy affects many cell types, including hematopoietic as well as non-hematopoietic …
autophagy affects many cell types, including hematopoietic as well as non-hematopoietic …
A brief history of autophagy from cell biology to physiology and disease
N Mizushima - Nature cell biology, 2018 - nature.com
The field of autophagy research has developed rapidly since the first description of the
process in the 1960s and the identification of autophagy genes in the 1990s. Autophagy is …
process in the 1960s and the identification of autophagy genes in the 1990s. Autophagy is …
Autophagy balances inflammation in innate immunity
Macroautophagy/autophagy is a homeostatic process with multiple effects on immunity. One
of the pivotal contributions of autophagy in immunity is the cell autonomous control of …
of the pivotal contributions of autophagy in immunity is the cell autonomous control of …
Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease
Inflammatory bowel disease (IBD) is associated with risk variants in the human genome and
dysbiosis of the gut microbiome, though unifying principles for these findings remain largely …
dysbiosis of the gut microbiome, though unifying principles for these findings remain largely …
Crosstalk between autophagy and inflammatory signalling pathways: balancing defence and homeostasis
K Cadwell - Nature Reviews Immunology, 2016 - nature.com
Autophagy has broad functions in immunity, ranging from cell-autonomous defence to
coordination of complex multicellular immune responses. The successful resolution of …
coordination of complex multicellular immune responses. The successful resolution of …
Autophagy and inflammation
Y Matsuzawa-Ishimoto, S Hwang… - Annual review of …, 2018 - annualreviews.org
The cellular degradative pathway of autophagy has a fundamental role in immunity. Here,
we review the function of autophagy and autophagy proteins in inflammation. We discuss …
we review the function of autophagy and autophagy proteins in inflammation. We discuss …
Autophagy restricts Mycobacterium tuberculosis during acute infection in mice
GR Golovkine, AW Roberts, HM Morrison… - Nature …, 2023 - nature.com
Whether or not autophagy has a role in defence against Mycobacterium tuberculosis
infection remains unresolved. Previously, conditional knockdown of the core autophagy …
infection remains unresolved. Previously, conditional knockdown of the core autophagy …
The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections
Virus infection induces different cellular responses in infected cells. These include cellular
stress responses like autophagy and unfolded protein response (UPR). Both autophagy and …
stress responses like autophagy and unfolded protein response (UPR). Both autophagy and …
Autophagy regulation of metabolism is required for CD8+ T cell anti-tumor immunity
L DeVorkin, N Pavey, G Carleton, A Comber, C Ho… - Cell reports, 2019 - cell.com
Autophagy is a cell survival process essential for the regulation of immune responses to
infections. However, the role of T cell autophagy in anti-tumor immunity is less clear. Here …
infections. However, the role of T cell autophagy in anti-tumor immunity is less clear. Here …
[HTML][HTML] Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production
J Xu, L Kong, BA Oliver, B Li, EA Creasey, G Guzman… - Cell reports, 2023 - cell.com
Autophagy is an essential cellular process that is deeply integrated with innate immune
signaling; however, studies that examine the impact of autophagic modulation in the context …
signaling; however, studies that examine the impact of autophagic modulation in the context …