Nitric oxide can interact with a wide range of proteins including many that are involved in
metabolism. In this review we have summarized the effects of NO on glycolysis, fatty acid …

Patients with heart failure (HF) usually present with skeletal muscle diseases of varying
severity, ranging from early fatigue on exercise to sarcopenia, sarcopenic obesity or …

Ageing is a natural ontogenetic phenomenon that entails a decrease in the adaptive
capacity of the organism, as a result of which the body becomes less adaptable to stressful …

Despite a growing number of successful therapies, heart failure remains the most common
cause of death and disability worldwide. Thus, new and novel therapeutic strategies are …

Chronic kidney disease (CKD) manifests with systemic inflammation, oxidative stress, and
gut dysbiosis, resulting in metabolic disorders and elevated rates of cardiovascular disease …

Heart failure (HF) results in a myriad of central and peripheral abnormalities that impair the
ability to sustain skeletal muscle contractions and, therefore, limit tolerance to exercise …

Menopause is associated with reduced nitric oxide bioavailability and vascular function.
Although exercise is known to improve vascular function, this is blunted in estrogen-deficient …

Previous studies have investigated the impact of dietary nitrate on vascular function due to
the association between dietary nitrate ingestion and improvement in nitric oxide (NO) …

Increasing knowledge of the processes leading to heart failure (HF) has allowed significant
developments in therapies for HF over the past few decades. Despite the evolution of HF …

Background/Objectives: Inorganic nitrate (NO3−) supplementation, via its conversion to nitric
oxide (NO), has been purported to be ergogenic in healthy individuals. Many disease states …