Knowledge integration and decision support for accelerated discovery of antibiotic resistance genes

J Youn, N Rai, I Tagkopoulos - Nature Communications, 2022 - nature.com
We present a machine learning framework to automate knowledge discovery through
knowledge graph construction, inconsistency resolution, and iterative link prediction. By …

DTKGIN: Predicting drug-target interactions based on knowledge graph and intent graph

Y Luo, G Duan, Q Zhao, X Bi, J Wang - Methods, 2024 - Elsevier
Abstract Knowledge graph intent graph attention mechanism Predicting drug-target
interactions (DTIs) plays a crucial role in drug discovery and drug development. Considering …

Biomedical Knowledge Graph: A Survey of Domains, Tasks, and Real-World Applications

Y Lu, SY Goi, X Zhao, J Wang - arxiv preprint arxiv:2501.11632, 2025 - arxiv.org
Biomedical knowledge graphs (BKGs) have emerged as powerful tools for organizing and
leveraging the vast and complex data found across the biomedical field. Yet, current reviews …

Petagraph: A large-scale unifying knowledge graph framework for integrating biomolecular and biomedical data

BJ Stear, T Mohseni Ahooyi, JA Simmons, C Kollar… - Scientific Data, 2024 - nature.com
Over the past decade, there has been substantial growth in both the quantity and complexity
of available biomedical data. In order to more efficiently harness this extensive data and …

[HTML][HTML] Predicting distant metastatic sites of cancer using perturbed correlations of miRNAs with competing endogenous RNAs

M Cho, B Park, K Han - Computational Biology and Chemistry, 2025 - Elsevier
Cancer metastasis is the dissemination of tumor cells from the primary tumor site to other
parts of the body via the lymph system or bloodstream. Metastasis is the leading cause of …

Predicting Distant Metastatic Sites in Cancer Using miRNA and mRNA Expression Data

D Mamatkarimov, J Kang, K Han - Current Bioinformatics, 2024 - benthamdirect.com
Background Cancer patients with metastasis face a much lower survival rate and a higher
risk of recurrence than those without metastasis. So far, several learning methods have been …

[KNJIGA][B] Unlocking Insights in the Life Sciences Domain Through Knowledge Graph Construction and Hypothesis Generation Using Machine Learning

JS Youn - 2024 - search.proquest.com
In the dynamic landscape of life sciences data, the inherent noise and lack of machine-
friendliness present significant challenges. The pressing need arises to transform this …