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Recent Developments in 14–3–3 Stabilizers for Regulating Protein–Protein Interactions: An Update
Y Tian, L Li, L Wu, Q Xu, Y Li, H Pan… - Journal of Medicinal …, 2025 - ACS Publications
14–3–3 proteins play a crucial role in the regulation of protein–protein interactions,
impacting various cellular processes and disease mechanisms. Recent advancements have …
impacting various cellular processes and disease mechanisms. Recent advancements have …
Automatically Defining Protein Words for Diverse Functional Predictions Based on Attention Analysis of a Protein Language Model
H Chen, B Tian, J Zhong, X Zhang, J Chen, L Guo… - bioRxiv, 2025 - biorxiv.org
Understanding the relationship between protein sequence and function remains a
longstanding challenge in bioinformatics, and to date the lion′ s share of related tools …
longstanding challenge in bioinformatics, and to date the lion′ s share of related tools …
Bioinformatics-Driven Structural and Pharmacological Analysis of SLITRK1 in Tourette Syndrome: Impact of S656M Mutation Using Molecular Dynamics, Docking, and …
SLITRK1 is a critical protein involved in neural development and is associated with various
neurological disorders, including Tourette Syndrome. This study investigates the structural …
neurological disorders, including Tourette Syndrome. This study investigates the structural …
The Evolving Landscape of Protein Allostery: From Computational and Experimental Perspectives
S Ekambaram, G Arakelov, NV Dokholyan - Available at SSRN 5120789 - papers.ssrn.com
Protein allostery is a fundamental biological regulatory mechanism that allows
communication between distant locations within a protein, modifying its function in response …
communication between distant locations within a protein, modifying its function in response …