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Ageing and multiple sclerosis
The factor that is most relevant and strongly associated with the clinical course of multiple
sclerosis is chronological age. Very young patients exclusively have relapsing remitting …
sclerosis is chronological age. Very young patients exclusively have relapsing remitting …
Epidemiology and pathophysiology of multiple sclerosis
Epidemiology and Pathophysiology of Multiple Sclerosis : CONTINUUM: Lifelong Learning in
Neurology Account Register Activate Subscription Help Subscribe American Academy of …
Neurology Account Register Activate Subscription Help Subscribe American Academy of …
Genetic variants associated with longitudinal changes in brain structure across the lifespan
Human brain structure changes throughout the lifespan. Altered brain growth or rates of
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …
Myelin in the central nervous system: structure, function, and pathology
C Stadelmann, S Timmler… - Physiological …, 2019 - journals.physiology.org
Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …
The role of glial cells in multiple sclerosis disease progression
Despite the development of highly effective treatments for relapsing–remitting multiple
sclerosis (MS), limited progress has been made in addressing primary progressive or …
sclerosis (MS), limited progress has been made in addressing primary progressive or …
Association of brain atrophy with disease progression independent of relapse activity in patients with relapsing multiple sclerosis
Importance The mechanisms driving neurodegeneration and brain atrophy in relapsing
multiple sclerosis (RMS) are not completely understood. Objective To determine whether …
multiple sclerosis (RMS) are not completely understood. Objective To determine whether …
Mechanism-based criteria to improve therapeutic outcomes in progressive multiple sclerosis
In contrast to the multiple disease-modifying therapies that are available for relapsing–
remitting multiple sclerosis (MS), the therapeutic options for progressive MS (PMS) are …
remitting multiple sclerosis (MS), the therapeutic options for progressive MS (PMS) are …
MAGNIMS consensus recommendations on the use of brain and spinal cord atrophy measures in clinical practice
Early evaluation of treatment response and prediction of disease evolution are key issues in
the management of people with multiple sclerosis (MS). In the past 20 years, MRI has …
the management of people with multiple sclerosis (MS). In the past 20 years, MRI has …
Epidemiology and treatment of multiple sclerosis in elderly populations
The prevalence of multiple sclerosis (MS) and the age of affected patients are increasing
owing to increased longevity of the general population and the availability of effective …
owing to increased longevity of the general population and the availability of effective …
Progression of regional grey matter atrophy in multiple sclerosis
Abstract See Stankoff and Louapre (doi: 10.1093/brain/awy114) for a scientific commentary
on this article. Grey matter atrophy is present from the earliest stages of multiple sclerosis …
on this article. Grey matter atrophy is present from the earliest stages of multiple sclerosis …