The prevalence of nonalcoholic steatohepatitis (NASH) is increasing worldwide, yet there
are no effective treatments. A decade has passed since the initial lipidomics analyses of liver …

The NR superfamily comprises 48 transcription factors in humans that control a plethora of
gene network programs involved in a wide range of physiologic processes. This review will …

Vitamin A is required for important physiological processes, including embryogenesis,
vision, cell proliferation and differentiation, immune regulation, and glucose and lipid …

Plasma metabolite concentrations reflect the activity of tissue metabolic pathways and their
quantitative determination may be informative about pathogenic conditions. We searched for …

Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease affecting up to 30% of the
general adult population. NAFLD encompasses a histological spectrum ranging from pure …

Obesity is increasing in an alarming rate worldwide, which causes higher risks of some
diseases, such as type 2 diabetes, cardiovascular diseases, and cancer. Current therapeutic …

Over the past decades, obesity has become a rising health problem as the accessibility to
high calorie, low nutritional value food has increased. Research shows that some bioactive …

Monascus-fermented red mold rice (RMR) has excellent physiological efficacy on lipid
metabolism and liver function. This study investigated the ameliorative effects of …

Lipids represent a very diverse group of compounds with a high variety of physicochemical
properties determining their functional activities. For omics-wide identification of lipid …

A deficiency in cystic fibrosis transmembrane conductance regulator (CFTR) function in CF
leads to chronic lung disease. CF is associated with abnormalities in fatty acids, ceramides …