To flourish, cancers greatly depend on their surrounding tumor microenvironment (TME),
and cancer-associated fibroblasts (CAFs) in TME are critical for cancer occurrence and …

Solid tumours comprise cancer cells that engage in continuous interactions with non-
malignant cells and with acellular components, forming the tumour microenvironment (TME) …

Simple Summary Cancer cells rely on the surrounding environment to grow and spread.
This environment contains structural components, secreted factors, immune cells, and other …

Animal models refers to the animal experimental objects and related materials that can
simulate human body established in medical research. As the second-largest disease in …

With the economy's globalization and the population's aging, cancer has become the
leading cause of death in most countries. While imposing a considerable burden on society …

Simple Summary To improve efficacy of solid cancer treatment, efforts have shifted towards
targeting both the cancer cells and the surrounding tumour tissue they grow in. The lysyl …

Rationale: Osteosarcoma (OS) is the most common primary bone tumor with a poor
prognosis, but the detailed mechanism is still unclear. A comprehensive investigation of …

Postoperative abdominal infectious complication (AIC) is associated with metastasis in
locally advanced gastric cancer (GC) patients after radical gastrectomy. However, the …

Metabolic reprogramming provides tumors with an energy source and biofuel to support
their survival in the malignant microenvironment. Extensive research into the intrinsic …

Tumors are equipped with a highly complex machinery of interrelated events so as to adapt
to hazardous conditions, preserve a growing cell mass and thrive at the site of metastasis …