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Spatially distinguished, multiplex nucleic acid analysis of biological specimens
A method for spatially tagging nucleic acids of a biological specimen, including steps of (a)
providing a solid support comprising different nucleic acid probes that are randomly located …
providing a solid support comprising different nucleic acid probes that are randomly located …
Spatially encoded biological assays
MS Chee - US Patent 11,733,238, 2023 - Google Patents
The present invention provides assays and assay systems for use in spatially encoded
biological assays. The invention provides an assay system comprising an assay capable of …
biological assays. The invention provides an assay system comprising an assay capable of …
Spatially encoded biological assays
MS Chee - US Patent 11,365,442, 2022 - Google Patents
The present invention provides assays and assay systems for use in spatially encoded
biological assays. The invention provides an assay system comprising an assay capable of …
biological assays. The invention provides an assay system comprising an assay capable of …
Spatially encoded biological assays
MS Chee - US Patent 11,384,386, 2022 - Google Patents
Related US Application Data Continuation of application No. 16/988,284, filed on Aug. 7,
2020, now Pat. No. 10,961,566, which is a continuation of application No. 16/414,213, filed …
2020, now Pat. No. 10,961,566, which is a continuation of application No. 16/414,213, filed …
Methods and systems for determining spatial patterns of biological targets in a sample
MS Chee, DA Routenberg - US Patent 11,753,674, 2023 - Google Patents
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …
Generating capture probes for spatial analysis
Y Yin, EPR Iyer, Z Bent, S Giacomello… - US Patent …, 2023 - Google Patents
2021-06-10 Assigned to 10X GENOMICS, INC. reassignment 10X GENOMICS, INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
Spatial assays with perturbed cells
EPR Iyer - US Patent 11,732,299, 2023 - Google Patents
NRJAVPSFFCBXDT-HUESYALOSA-N 1, 2-distearoyl-sn-glycero-3-phosphocholine
Chemical compound CCCCCCCCCCCCCCCCCC (= O) OC [C@ H](COP ([O-])(= O) OCC …
Chemical compound CCCCCCCCCCCCCCCCCC (= O) OC [C@ H](COP ([O-])(= O) OCC …
Methods of making gene expression libraries
LJA Martinez, EPR Iyer - US Patent 11,891,654, 2024 - Google Patents
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …
Methods and compositions for partitioning a biological sample
FA Bava - US Patent 11,835,462, 2023 - Google Patents
US11835462B2 - Methods and compositions for partitioning a biological sample - Google
Patents US11835462B2 - Methods and compositions for partitioning a biological sample …
Patents US11835462B2 - Methods and compositions for partitioning a biological sample …
Increasing efficiency of spatial analysis in a biological sample
FA Bava - US Patent 11,732,300, 2023 - Google Patents
Disclosed herein are methods of amplifying an analyte in a biological sample using a
bridging oligonucleotide that hybridizes to a captured analyte. The methods disclosed …
bridging oligonucleotide that hybridizes to a captured analyte. The methods disclosed …