Age-related macular degeneration

CJ Thomas, RG Mirza, MK Gill - Medical Clinics, 2021 - medical.theclinics.com
Background AMD involves pathologic changes to the deeper retinal layers of the macula
and surrounding vasculature resulting in central vision loss. The accumulation of retinal …

Age-related macular degeneration

P Mitchell, G Liew, B Gopinath, TY Wong - The Lancet, 2018 - thelancet.com
Age-related macular degeneration is a leading cause of visual impairment and severe vision
loss. Clinically, it is classified as early-stage (medium-sized drusen and retinal pigmentary …

[HTML][HTML] Age-related macular degeneration: Epidemiology, genetics, pathophysiology, diagnosis, and targeted therapy

Y Deng, L Qiao, M Du, C Qu, L Wan, J Li, L Huang - Genes & diseases, 2022 - Elsevier
Age-related macular degeneration (AMD) is a complex eye disorder and is the leading
cause of incurable blindness worldwide in the elderly. Clinically, AMD initially affects the …

Risk factors for progression of age‐related macular degeneration

TJ Heesterbeek, L Lorés‐Motta… - Ophthalmic and …, 2020 - Wiley Online Library
Purpose Age‐related macular degeneration (AMD) is a degenerative disease of the macula,
often leading to progressive vision loss. The rate of disease progression can vary among …

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

LG Fritsche, W Igl, JNC Bailey, F Grassmann… - Nature …, 2016 - nature.com
Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the
elderly, with limited therapeutic options. Here we report on a study of> 12 million variants …

Recent developments in age-related macular degeneration: a review

WM Al-Zamil, SA Yassin - Clinical interventions in aging, 2017 - Taylor & Francis
Background Visual impairment in elderly people is a considerable health problem that
significantly affects quality of life of millions worldwide. The magnitude of this issue is …

[HTML][HTML] A deep learning algorithm for prediction of age-related eye disease study severity scale for age-related macular degeneration from color fundus photography

F Grassmann, J Mengelkamp, C Brandl, S Harsch… - Ophthalmology, 2018 - Elsevier
Purpose Age-related macular degeneration (AMD) is a common threat to vision. While
classification of disease stages is critical to understanding disease risk and progression …

Epidemiology of age-related macular degeneration (AMD): associations with cardiovascular disease phenotypes and lipid factors

KL Pennington, MM DeAngelis - Eye and vision, 2016 - Springer
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
adults over 50 years old. Genetic, epidemiological, and molecular studies are beginning to …

Age-related macular degeneration: a review

M Fleckenstein, S Schmitz-Valckenberg… - JAMA, 2024 - jamanetwork.com
Importance Age-related macular degeneration (AMD) affects approximately 20 million
people in the US and 196 million people worldwide. AMD is a leading cause of severe …

Age-related macular degeneration preferred practice pattern®

CJ Flaxel, RA Adelman, ST Bailey, A Fawzi, JI Lim… - …, 2020 - aaojournal.org
Background: Age-related macular degeneration is a leading cause of severe, irreversible
vision impairment in developed countries. The primary risk factors for the development of …