The cerebral oxygen cascade includes three key stages:(a) convective oxygen delivery
representing the bulk flow of oxygen to the cerebral vascular bed;(b) diffusion of oxygen from …

Cardiac arrest (CA) is a major cause of morbidity and mortality frequently associated with
neurological and systemic involvement. Supportive therapeutic strategies such as …

Survival to hospital discharge among patients with out-of-hospital cardiac arrest (OHCA) is
low and important regional differences in treatment practices and survival have been …

Background Hyperoxemia may aggravate reperfusion brain injury after cardiac arrest. The
aim of this study was to study the associations between different levels of hyperoxemia in the …

Background. Devices for mechanical cardiopulmonary resuscitation (CPR) are
recommended when high quality CPR cannot be provided. Different devices are available …

Introduction Although largely used, the place of oxygen therapy and its devices in patients
with acute hypoxemic respiratory failure (ARF) deserves to be clarified. The French Intensive …

Abstract Background Veno-arterial Extracorporeal Membrane Oxygenation (VA-ECMO) is a
rescue treatment in refractory cardiogenic shock (CS) or refractory cardiac arrest (CA) …

Background In acute brain injury (ABI), the effects of hypoxemia as a potential cause of
secondary brain damage and poor outcome are well documented, whereas the impact of …

Although direct data to guide mechanical ventilation in brain-injured patients is
accumulating, the current evidence base remains limited. Ventilatory considerations in this …

In-hospital cardiac arrest (IHCA) is associated with high mortality and poor neurological
outcomes. Our objective was to assess whether the lactate-to-albumin ratio (LAR) can …