Polymeric nanoparticles for drug delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Tumor abnormality-oriented nanomedicine design

Q Zhou, J **ang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

PEGylated lipid nanoparticle formulations: immunological safety and efficiency perspective

R Tenchov, JM Sasso, QA Zhou - Bioconjugate chemistry, 2023 - ACS Publications
Lipid nanoparticles (LNPs) have been recognized as efficient vehicles to transport a large
variety of therapeutics. Currently in the spotlight as important constituents of the COVID-19 …

Liposomes in cancer therapy: how did we start and where are we now

MD Fulton, W Najahi-Missaoui - International Journal of Molecular …, 2023 - mdpi.com
Since their first discovery in the 1960s by Alec Bangham, liposomes have been shown to be
effective drug delivery systems for treating various cancers. Several liposome-based …

Methods of liposomes preparation: formation and control factors of versatile nanocarriers for biomedical and nanomedicine application

D Lombardo, MA Kiselev - Pharmaceutics, 2022 - mdpi.com
Liposomes are nano-sized spherical vesicles composed of an aqueous core surrounded by
one (or more) phospholipid bilayer shells. Owing to their high biocompatibility, chemical …

Polymeric nanoparticles for delivery of natural bioactive agents: recent advances and challenges

M Elmowafy, K Shalaby, MH Elkomy, OA Alsaidan… - Polymers, 2023 - mdpi.com
In the last few decades, several natural bioactive agents have been widely utilized in the
treatment and prevention of many diseases owing to their unique and versatile therapeutic …

Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine

MS de Almeida, E Susnik, B Drasler… - Chemical society …, 2021 - pubs.rsc.org
Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …

Nanoparticle protein corona: from structure and function to therapeutic targeting

G Bashiri, MS Padilla, KL Swingle, SJ Shepherd… - Lab on a Chip, 2023 - pubs.rsc.org
Nanoparticle (NP)-based therapeutics have ushered in a new era in translational medicine.
However, despite the clinical success of NP technology, it is not well-understood how NPs …

Stealth nanoparticles in oncology: Facing the PEG dilemma

S Zalba, TLM Ten Hagen, C Burgui… - Journal of Controlled …, 2022 - Elsevier
Nanoparticles (Nps) have revolutionized the landscape of many treatments, by modifying not
only pharmacokinetic properties of the encapsulated agent, but also providing a significant …

Biodegradable polymeric nanoparticles for drug delivery to solid tumors

A Gagliardi, E Giuliano, E Venkateswararao… - Frontiers in …, 2021 - frontiersin.org
Advances in nanotechnology have favored the development of novel colloidal formulations
able to modulate the pharmacological and biopharmaceutical properties of drugs. The …