Beyond the GFAP-astrocyte protein markers in the brain
AM Jurga, M Paleczna, J Kadluczka, KZ Kuter - Biomolecules, 2021 - mdpi.com
The idea of central nervous system as one-man band favoring neurons is long gone. Now
we all are aware that neurons and neuroglia are team players and constant communication …
we all are aware that neurons and neuroglia are team players and constant communication …
Neural stem cells in the adult spinal cord
Spinal cord injury results in cell loss, disruption of neural circuitry and chronic functional
impairment. Several different cell types generate progeny in response to injury, which …
impairment. Several different cell types generate progeny in response to injury, which …
An ependymal cell census identifies heterogeneous and ongoing cell maturation in the adult mouse spinal cord that changes dynamically on injury
The adult spinal cord stem cell potential resides within the ependymal cell population and
declines with age. Ependymal cells are, however, heterogeneous, and the biological …
declines with age. Ependymal cells are, however, heterogeneous, and the biological …
Nestin-and doublecortin-positive cells reside in adult spinal cord meninges and participate in injury-induced parenchymal reaction
Adult spinal cord has little regenerative potential, thus limiting patient recovery following
injury. In this study, we describe a new population of cells resident in the adult rat spinal cord …
injury. In this study, we describe a new population of cells resident in the adult rat spinal cord …
[HTML][HTML] Salamander spinal cord regeneration: The ultimate positive control in vertebrate spinal cord regeneration
A Tazaki, EM Tanaka, JF Fei - Developmental biology, 2017 - Elsevier
Repairing injured tissues/organs is one of the major challenges for the maintenance of
proper organ function in adulthood. In mammals, the central nervous system including the …
proper organ function in adulthood. In mammals, the central nervous system including the …
Fgf2 improves functional recovery—decreasing gliosis and increasing radial glia and neural progenitor cells after spinal cord injury
Objectives A major impediment for recovery after mammalian spinal cord injury (SCI) is the
glial scar formed by proliferating reactive astrocytes. Finding factors that may reduce glial …
glial scar formed by proliferating reactive astrocytes. Finding factors that may reduce glial …
Single-cell RNA sequencing reveals Nestin+ active neural stem cells outside the central canal after spinal cord injury
M Shu, X Xue, H Nie, X Wu, M Sun, L Qiao, X Li… - Science China Life …, 2022 - Springer
Neural stem cells (NSCs) in the spinal cord hold great potential for repair after spinal cord
injury (SCI). The ependyma in the central canal (CC) region has been considered as the …
injury (SCI). The ependyma in the central canal (CC) region has been considered as the …
Employing endogenous NSCs to promote recovery of spinal cord injury
S Liu, Z Chen - Stem cells international, 2019 - Wiley Online Library
Endogenous neural stem cells (NSCs) exist in the central canal of mammalian spinal cords.
Under normal conditions, these NSCs remain quiescent and express FoxJ1. After spinal …
Under normal conditions, these NSCs remain quiescent and express FoxJ1. After spinal …
Low‐density lipoprotein receptor‐related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation
D Safina, F Schlitt, R Romeo, T Pflanzner, CU Pietrzik… - Glia, 2016 - Wiley Online Library
The LDL family of receptors and its member low‐density lipoprotein receptor‐related protein
1 (LRP1) have classically been associated with a modulation of lipoprotein metabolism …
1 (LRP1) have classically been associated with a modulation of lipoprotein metabolism …
The ependymal region of the adult human spinal cord differs from other species and shows ependymoma-like features
Several laboratories have described the existence of undifferentiated precursor cells that
may act like stem cells in the ependyma of the rodent spinal cord. However, there are reports …
may act like stem cells in the ependyma of the rodent spinal cord. However, there are reports …