Map** sign-tracking and goal-tracking onto human behaviors

JM Colaizzi, SB Flagel, MA Joyner… - Neuroscience & …, 2020 - Elsevier
As evidenced through classic Pavlovian learning mechanisms, environmental cues can
become incentivized and influence behavior. These stimulus-outcome associations are …

[書籍][B] Using heterogeneous stocks for fine-map** genetically complex traits

LC Solberg Woods, AA Palmer - 2019 - Springer
In this chapter we will review both the rationale and experimental design for using
Heterogeneous Stock (HS) populations for fine-map** of complex traits in mice and rats …

Sign tracking, but not goal tracking, is resistant to outcome devaluation

SE Morrison, MA Bamkole, SM Nicola - Frontiers in neuroscience, 2015 - frontiersin.org
During Pavlovian conditioning, a conditioned stimulus (CS) may act as a predictor of a
reward to be delivered in another location. Individuals vary widely in their propensity to …

Rats that sign-track are resistant to Pavlovian but not instrumental extinction

AM Ahrens, BF Singer, CJ Fitzpatrick, JD Morrow… - Behavioural brain …, 2016 - Elsevier
Individuals vary in the extent to which they attribute incentive salience to a discrete cue
(conditioned stimulus; CS) that predicts reward delivery (unconditioned stimulus; US), which …

Individual variation in the motivational and neurobiological effects of an opioid cue

LM Yager, KK Pitchers, SB Flagel… - …, 2015 - nature.com
A discrete cue associated with intravenous injections of cocaine acquires greater control
over motivated behavior in some rats ('sign-trackers', STs) than others ('goal-trackers', GTs) …

Isolating the incentive salience of reward-associated stimuli: value, choice, and persistence

JS Beckmann, JJ Chow - Learning & memory, 2015 - learnmem.cshlp.org
Sign-and goal-tracking are differentially associated with drug abuse-related behavior.
Recently, it has been hypothesized that sign-and goal-tracking behavior are mediated by …

Individual variation in the propensity to attribute incentive salience to a food cue: influence of sex

KK Pitchers, SB Flagel, EG O'Donnell… - Behavioural brain …, 2015 - Elsevier
There is considerable individual variation in the propensity of animals to attribute incentive
salience to discrete reward cues, but to date most of this research has been conducted in …

The neuroscience of cognitive-motivational styles: Sign-and goal-trackers as animal models.

M Sarter, KB Phillips - Behavioral neuroscience, 2018 - psycnet.apa.org
Cognitive-motivational styles describe predominant patterns of processing or biases that
broadly influence human cognition and performance. Here we focus on the impact of …

Incentive salience attribution,“sensation-seeking” and “novelty-seeking” are independent traits in a large sample of male and female heterogeneous stock rats

AR Hughson, AP Horvath, K Holl, AA Palmer… - Scientific reports, 2019 - nature.com
There are a number of traits that are thought to increase susceptibility to addiction, and some
of these are modeled in preclinical studies. For example,“sensation-seeking” is predictive of …

Revisiting the validity of the mouse tail suspension test: Systematic review and meta-analysis of the effects of prototypic antidepressants

Y Stukalin, A Lan, H Einat - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Animal models in neuropsychiatric research need validation. One way to address external
validity is systematic reviews and meta-analyses. The present study presents a meta …