Clinical and experimental insight into pathophysiology, comorbidity and therapy of absence seizures

V Crunelli, ML Lőrincz, C McCafferty, RC Lambert… - Brain, 2020 - academic.oup.com
Absence seizures in children and teenagers are generally considered relatively benign
because of their non-convulsive nature and the large incidence of remittance in early …

Cognitive and neurodevelopmental comorbidities in paediatric epilepsy

KC Nickels, MJ Zaccariello, LD Hamiwka… - Nature Reviews …, 2016 - nature.com
Cognitive and behavioural comorbidities are often seen in children with epilepsy, and are
more common and severe in refractory epilepsy. These comorbidities are associated with …

ILAE definition of the idiopathic generalized epilepsy syndromes: position statement by the ILAE task force on nosology and definitions

E Hirsch, J French, IE Scheffer, A Bogacz, T Alsaadi… - …, 2022 - Wiley Online Library
Abstract In 2017, the International League Against Epilepsy (ILAE) Classification of
Epilepsies described the “genetic generalized epilepsies”(GGEs), which contained the …

Common psychiatric comorbidities in epilepsy: How big of a problem is it?

JA Salpekar, M Mula - Epilepsy & behavior, 2019 - Elsevier
Psychiatric illness and epilepsy commonly co-occur in adults and in children and
adolescents. Theories of comorbidity are complex, but recurring associations between the …

Central serotonin-2A (5-HT2A) receptor dysfunction in depression and epilepsy: the missing link?

BP Guiard, GD Giovanni - Frontiers in pharmacology, 2015 - frontiersin.org
5-Hydroxytryptamine 2A receptors (5-HT2A-Rs) are G-protein coupled receptors. In
agreement with their location in the brain, they have been implicated not only in various …

Systematic review and meta-analysis of anxiety and depression in youth with epilepsy

AJ Scott, L Sharpe, M Loomes… - Journal of pediatric …, 2020 - academic.oup.com
Objective The aim of this systematic review and meta-analysis was to provide an estimate of
the prevalence of anxiety and depressive disorders in youth with epilepsy (YWE). It also …

Ethosuximide reduces epileptogenesis and behavioral comorbidity in the GAERS model of genetic generalized epilepsy

G Dezsi, E Ozturk, D Stanic, KL Powell… - …, 2013 - Wiley Online Library
Purpose Ethosuximide (ESX) is a drug of choice for the symptomatic treatment of absence
seizures. Chronic treatment with ESX has been reported to have disease‐modifying …

Epilepsy and its main psychiatric comorbidities in adults and children

A Verrotti, D Carrozzino, M Milioni, M Minna… - Journal of the …, 2014 - Elsevier
Psychiatric disorders seem to be more frequent in patients with epilepsy (PWE) than the
general population. Although researchers have documented a strong association between …

The current state of absence epilepsy: can we have your attention? the current state of absence epilepsy

JR Tenney, TA Glauser - Epilepsy currents, 2013 - journals.sagepub.com
Absence seizures are common within many different epilepsies and span all the ages. Even
though absence seizures were described more than three centuries ago advances …

Long‐term seizure remission in childhood absence epilepsy: might initial treatment matter?

AT Berg, SR Levy, FM Testa, H Blumenfeld - Epilepsia, 2014 - Wiley Online Library
Objective Examine the possible association between long‐term seizure outcome in
childhood absence epilepsy (CAE) and the initial treatment choice. Methods Children with …