Despite recent advances in iron chelation therapy, excess iron deposition in pituitary
gonadotropic cells remains one of the major problems in thalassemic patients …

Case 1. Kierra Malcom,† a 17 year old with homozygous sickle cell disease (HbSS), was on
chronic erythrocytapheresis after she suffered a stroke at 8 years of age. With the …

Long-term complications after hematopoietic cell transplantation (HCT) have been studied in
detail. Although virtually every organ system can be adversely affected after HCT, the …

Results During early childhood, patients showed lower mean SD scores (SDS) for height (−
1.7) and a markedly elevated sitting height index (ratio of sitting height to total body height) …

Introduction Patients with beta thalassemia major (TM) have a higher risk of diabetes and an
abnormal oral glucose tolerance test (OGTT), but there is no single agree monitoring …

Background Thalassaemia is a recessively‐inherited blood disorder that leads to anaemia
of varying severity. In those affected by the more severe forms, regular blood transfusions …

Background Short stature is a frequent complication after pediatric kidney transplantation
(KT). Whether the type of transplantation and prior treatment with recombinant human …

An improvement in quality of life and survival occurred among thalassemia major (TM)
patients: pregnancy in such patients has become a reality. Safe pregnancy and delivery …

Objectives With improved access to intrauterine transfusion (IUT), more fetuses with
haemoglobin Bart's hydrops fetalis (HBHF; homozygous α0-thalassaemia) will survive …

In thalassaemic patients, multiple organ systems may be affected by the disease, blood
transfusion, iron overload and chelating therapy. Patients may develop cardiomyopathy …