Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications

J Mondal, S Pillarisetti, V Junnuthula, M Saha… - Journal of Controlled …, 2023 - Elsevier
Exosomes are endosome-derived nanovesicles involved in cellular communication. They
are natural nanocarriers secreted by various cells, making them suitable candidates for …

Development of extracellular vesicle therapeutics: Challenges, considerations, and opportunities

B Claridge, J Lozano, QH Poh… - Frontiers in Cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) hold great promise as therapeutic modalities due to their
endogenous characteristics, however, further bioengineering refinement is required to …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

mRNA-based vaccines and therapeutics for COVID-19 and future pandemics

VP Chavda, S Soni, LK Vora, S Soni, A Khadela… - Vaccines, 2022 - mdpi.com
An unheard mobilization of resources to find SARS-CoV-2 vaccines and therapies has been
sparked by the COVID-19 pandemic. Two years ago, COVID-19's launch propelled mRNA …

Biological properties of milk-derived extracellular vesicles and their physiological functions in infant

X Jiang, L You, Z Zhang, X Cui, H Zhong… - Frontiers in Cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) are released by all cells under pathological and physiological
conditions. EVs harbor various biomolecules, including protein, lipid, non-coding RNA …

Artificial intelligence in medical science: a review

S Bindra, R Jain - Irish Journal of Medical Science (1971-), 2024 - Springer
Artificial intelligence (AI) is a technique to make intelligent machines, mainly by using smart
computer programs. It is based on a statistical analysis of data or machine learning. Using …

Milk/colostrum exosomes: A nanoplatform advancing delivery of cancer therapeutics

M Wallen, F Aqil, W Spencer, RC Gupta - Cancer letters, 2023 - Elsevier
Chemotherapeutics continue to play a central role in the treatment of a wide variety of
cancers. Conventional chemotherapy involving bolus intravenous doses results in severe …

Advances in lipid-based carriers for cancer therapeutics: Liposomes, exosomes and hybrid exosomes

DN Moholkar, R Kandimalla, RC Gupta, F Aqil - Cancer Letters, 2023 - Elsevier
Cancer has recently surpassed heart disease as the leading cause of deaths worldwide for
the age group 45–65 and has been the primary focus for biomedical researchers. Presently …

Exosomes as emerging drug delivery and diagnostic modality for breast cancer: recent advances in isolation and application

DN Kumar, A Chaudhuri, F Aqil, D Dehari, R Munagala… - Cancers, 2022 - mdpi.com
Simple Summary Breast cancer is considered the second most occurring cancer after lung
cancer globally. The treatment for breast cancer includes surgery, radiation, chemotherapy …

Extracellular vesicles: Emerging anti-cancer drugs and advanced functionalization platforms for cancer therapy

M Wu, M Wang, H Jia, P Wu - Drug Delivery, 2022 - Taylor & Francis
Increasing evidences show that unmodified extracellular vesicles (EVs) derived from various
cells can effectively inhibit the malignant progression of different types of tumors by …