Advanced microfluidic technologies for lipid nano-microsystems from synthesis to biological application

BG Carvalho, BT Ceccato, M Michelon, SW Han… - Pharmaceutics, 2022 - mdpi.com
Microfluidics is an emerging technology that can be employed as a powerful tool for
designing lipid nano-microsized structures for biological applications. Those lipid structures …

Recent Advances in Microfluidic Technologies for the Construction of Artificial Cells

S Tan, Y Ai, X Yin, Z Xue, X Fang… - Advanced Functional …, 2023 - Wiley Online Library
Artificial cells are synthetic constructs that emulate natural cells, with potential applications in
areas of energy science, environmental treatment, and the study of life's origins …

Artificial cell synthesis using biocatalytic polymerization-induced self-assembly

A Belluati, S Jimaja, RJ Chadwick, C Glynn… - Nature Chemistry, 2024 - nature.com
Artificial cells are biomimetic microstructures that mimic functions of natural cells, can be
applied as building blocks for molecular systems engineering, and host synthetic biology …

Spatiotemporal control of signal-driven enzymatic reaction in artificial cell-like polymersomes

H Seo, H Lee - Nature communications, 2022 - nature.com
Living cells can spatiotemporally control biochemical reactions to dynamically assemble
membraneless organelles and remodel cytoskeleton. Herein, we present a microfluidic …

Biocatalytic self-assembled synthetic vesicles and coacervates: From single compartment to artificial cells

D Gaur, NC Dubey, BP Tripathi - Advances in Colloid and Interface Science, 2022 - Elsevier
Compartmentalization is an intrinsic feature of living cells that allows spatiotemporal control
over the biochemical pathways expressed in them. Over the years, a library of …

Polymersome Membrane Engineering with Active Targeting or Controlled Permeability for Responsive Drug Delivery

A Kayani, A Raza, J Si, D Dutta, Q Zhou… - Biomacromolecules, 2023 - ACS Publications
Polymersomes have been extensively investigated for drug delivery as nanocarriers for two
decades due to a series of advantages including high stability under physiological …

High‐Precision Synthesis of RNA‐Loaded Lipid Nanoparticles for Biomedical Applications

H Seo, L Jeon, J Kwon, H Lee - Advanced Healthcare …, 2023 - Wiley Online Library
The recent development of RNA‐based therapeutics in delivering nucleic acids for gene
editing and regulating protein translation has led to the effective treatment of various …

Trends in the synthesis of polymer nano‐and microscale materials for bio‐related applications

JP Coats, R Cochereau, IA Dinu… - Macromolecular …, 2023 - Wiley Online Library
Polymeric nano‐and microscale materials bear significant potential in manifold applications
related to biomedicine. This is owed not only to the large chemical diversity of the constituent …

Polymersomes as the Next Attractive Generation of Drug Delivery Systems: Definition, Synthesis and Applications

M Fonseca, I Jarak, F Victor, C Domingues, F Veiga… - Materials, 2024 - mdpi.com
Polymersomes are artificial nanoparticles formed by the self-assembly process of
amphiphilic block copolymers composed of hydrophobic and hydrophilic blocks. They can …

Emerging Designs and Applications for Biomembrane Biosensors

E Selivanovitch, A Ostwalt, Z Chao… - Annual Review of …, 2024 - annualreviews.org
Nature has inspired the development of biomimetic membrane sensors in which the
functionalities of biological molecules, such as proteins and lipids, are harnessed for …