Anticancer agents are critical for the cancer treatment, but side effects and the drug
resistance associated with the currently used anticancer agents create an urgent need to …

Lung cancer is the most common malignancy and leads to around one-quarter of all cancer
deaths. Great advances have been achieved in the treatment of lung cancer with novel …

Cancer chemotherapy is frequently hampered by drug resistance, so the resistance to
anticancer agents represents one of the major obstacles for the effective cancer treatment …

The isatin framework is a useful template for the development of novel anticancer agents.
This is exemplified by the fact that several isatin‐based anticancer agents, such as …

Molecular hybridization is one of the recent stratagems in medicinal chemistry to synthesize
a novel hybrid molecule having better affinity and efficacy by combining two or more …

Dimerization is a promising strategy to develop novel drug candidates that could extend the
biological spectrum, enhance the activity, overcome drug resistance, as well as improve …

Acquired immune deficiency syndrome (AIDS)/human immunodeficiency virus (HIV) is one
of the largest and most devastating public health pandemics throughout the world. The …

Abstract Heterocyclic compounds containing 1, 2, 3‐triazole and isatin as core structures
have emerged as promising drug candidates due to their diverse biological activities such …

A series of dihydropyrimidine analogues were prepared via one‐pot Biginelli three‐
component condensation reaction and characterized by NMR, FT‐IR, MS spectra, and …

Twenty propylene and butylene tethered di‐isatin heteronuclear compounds 5a‐t were
synthesized, and their antibacterial activities were evaluated. Most of the synthesized di …