[HTML][HTML] Curcumin-loaded alginate hydrogels for cancer therapy and wound healing applications: A review
Hydrogels have emerged as a versatile platform for a numerous biomedical application due
to their ability to absorb a huge quantity of biofluids. In order to design hydrogels, natural …
to their ability to absorb a huge quantity of biofluids. In order to design hydrogels, natural …
Curcumin mediates anticancer effects by modulating multiple cell signaling pathways
Curcumin, a component of a spice native to India, was first isolated in 1815 by Vogel and
Pelletier from the rhizomes of Curcuma longa (turmeric) and, subsequently, the chemical …
Pelletier from the rhizomes of Curcuma longa (turmeric) and, subsequently, the chemical …
The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …
level. First, the interactions between curcumin and its molecular targets are addressed on …
The targets of curcumin
H Zhou, CS Beevers, S Huang - Current drug targets, 2011 - ingentaconnect.com
Curcumin (diferuloylmethane), an orange-yellow component of turmeric or curry powder, is a
polyphenol natural product isolated from the rhizome of the plant Curcuma longa. For …
polyphenol natural product isolated from the rhizome of the plant Curcuma longa. For …
Anticancer properties of medicinal plants and their bioactive compounds against breast cancer: a review on recent investigations
Breast cancer (BC) is one of the most common and recurring diseases and the second
leading cause of death in women. Despite prevention, diagnostics, and therapeutic options …
leading cause of death in women. Despite prevention, diagnostics, and therapeutic options …
[HTML][HTML] Efficacy and safety of curcumin in combination with paclitaxel in patients with advanced, metastatic breast cancer: A comparative, randomized, double-blind …
T Saghatelyan, A Tananyan, N Janoyan, A Tadevosyan… - Phytomedicine, 2020 - Elsevier
Background: The clinical efficacy of curcumin has not yet been established for the treatment
of cancer, despite a large body of evidence from numerous preclinical studies suggesting …
of cancer, despite a large body of evidence from numerous preclinical studies suggesting …
[HTML][HTML] Curcumin induces mitochondrial apoptosis in human hepatoma cells through BCLAF1-mediated modulation of PI3K/AKT/GSK-3β signaling
C Bai, J Zhao, J Su, J Chen, X Cui, M Sun, X Zhang - Life Sciences, 2022 - Elsevier
Curcumin is a yellow pigment extracted from the rhizome of turmeric, a traditional Chinese
medicine. Here, we tested the hypothesis that curcumin-mediated downregulation of …
medicine. Here, we tested the hypothesis that curcumin-mediated downregulation of …
Curcumin inhibits proliferation of breast cancer cells through Nrf2-mediated down-regulation of Fen1 expression
B Chen, Y Zhang, Y Wang, J Rao, X Jiang… - The Journal of steroid …, 2014 - Elsevier
Curcumin can inhibit cell proliferation of breast cancer, but the mechanism for this inhibition
remains unclear. Over-expression of Flap endonuclease 1 (Fen1), a DNA repair-specific …
remains unclear. Over-expression of Flap endonuclease 1 (Fen1), a DNA repair-specific …
[HTML][HTML] Natural products for chemoprevention of breast cancer
EY Ko, A Moon - Journal of cancer prevention, 2015 - ncbi.nlm.nih.gov
Breast cancer is the primary cause of cancer death in women. Although current therapies
have shown some promise against breast cancer, there is still no effective cure for the …
have shown some promise against breast cancer, there is still no effective cure for the …
Rational design of multifunctional dendritic mesoporous silica nanoparticles to load curcumin and enhance efficacy for breast cancer therapy
Breast cancer is the primary reason for cancer-related death in women worldwide and the
development of new formulations to treat breast cancer patients is crucial. Curcumin (Cur), a …
development of new formulations to treat breast cancer patients is crucial. Curcumin (Cur), a …