[HTML][HTML] Curcumin-loaded alginate hydrogels for cancer therapy and wound healing applications: A review

A Sood, A Dev, SS Das, HJ Kim, A Kumar… - International journal of …, 2023 - Elsevier
Hydrogels have emerged as a versatile platform for a numerous biomedical application due
to their ability to absorb a huge quantity of biofluids. In order to design hydrogels, natural …

Curcumin mediates anticancer effects by modulating multiple cell signaling pathways

AB Kunnumakkara, D Bordoloi, C Harsha… - Clinical …, 2017 - portlandpress.com
Curcumin, a component of a spice native to India, was first isolated in 1815 by Vogel and
Pelletier from the rhizomes of Curcuma longa (turmeric) and, subsequently, the chemical …

The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer

M Heger, RF van Golen, M Broekgaarden… - Pharmacological …, 2014 - Elsevier
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

The targets of curcumin

H Zhou, CS Beevers, S Huang - Current drug targets, 2011 - ingentaconnect.com
Curcumin (diferuloylmethane), an orange-yellow component of turmeric or curry powder, is a
polyphenol natural product isolated from the rhizome of the plant Curcuma longa. For …

Anticancer properties of medicinal plants and their bioactive compounds against breast cancer: a review on recent investigations

MI Khan, A Bouyahya, NEL Hachlafi, NE Menyiy… - … Science and Pollution …, 2022 - Springer
Breast cancer (BC) is one of the most common and recurring diseases and the second
leading cause of death in women. Despite prevention, diagnostics, and therapeutic options …

[HTML][HTML] Efficacy and safety of curcumin in combination with paclitaxel in patients with advanced, metastatic breast cancer: A comparative, randomized, double-blind …

T Saghatelyan, A Tananyan, N Janoyan, A Tadevosyan… - Phytomedicine, 2020 - Elsevier
Background: The clinical efficacy of curcumin has not yet been established for the treatment
of cancer, despite a large body of evidence from numerous preclinical studies suggesting …

[HTML][HTML] Curcumin induces mitochondrial apoptosis in human hepatoma cells through BCLAF1-mediated modulation of PI3K/AKT/GSK-3β signaling

C Bai, J Zhao, J Su, J Chen, X Cui, M Sun, X Zhang - Life Sciences, 2022 - Elsevier
Curcumin is a yellow pigment extracted from the rhizome of turmeric, a traditional Chinese
medicine. Here, we tested the hypothesis that curcumin-mediated downregulation of …

Curcumin inhibits proliferation of breast cancer cells through Nrf2-mediated down-regulation of Fen1 expression

B Chen, Y Zhang, Y Wang, J Rao, X Jiang… - The Journal of steroid …, 2014 - Elsevier
Curcumin can inhibit cell proliferation of breast cancer, but the mechanism for this inhibition
remains unclear. Over-expression of Flap endonuclease 1 (Fen1), a DNA repair-specific …

[HTML][HTML] Natural products for chemoprevention of breast cancer

EY Ko, A Moon - Journal of cancer prevention, 2015 - ncbi.nlm.nih.gov
Breast cancer is the primary cause of cancer death in women. Although current therapies
have shown some promise against breast cancer, there is still no effective cure for the …

Rational design of multifunctional dendritic mesoporous silica nanoparticles to load curcumin and enhance efficacy for breast cancer therapy

J Wang, Y Wang, Q Liu, L Yang, R Zhu… - … applied materials & …, 2016 - ACS Publications
Breast cancer is the primary reason for cancer-related death in women worldwide and the
development of new formulations to treat breast cancer patients is crucial. Curcumin (Cur), a …