Age-related macular degeneration (AMD) is a largely incurable disease and an emerging
problem in aging societies. It occurs in two forms, dry and wet (exudative, neovascular) …

Angiogenesis and immunosuppression are closely related pathophysiologic processes.
Widely prescribed in malignant tumor and proliferative retinal lesions, VEGF signaling …

Thrombotic microangiopathies (TMAs) have in common a terminal phenotype of
microangiopathic hemolytic anemia with end-organ dysfunction. Thrombotic …

Identification of novel immune biomarkers to gauge the underlying pathology and severity of
COVID-19 has been difficult due to the lack of longitudinal studies. Here, we analyzed serum …

Drug-induced kidney diseases represent a wide range of diseases that are responsible for a
significant proportion of all acute kidney injuries and chronic kidney diseases. In the present …

Growth factors are a class of proteins that play a role in the proliferation (the increase in the
number of cells resulting from cell division) and differentiation (when a cell undergoes …

Intravitreal vascular endothelial growth factor (VEGF) receptor blockade is used for a variety
of retinal pathologies. These include age-related macular degeneration (AMD), diabetic …

Acute kidney injury (AKI) is a clinical syndrome where a rapid decrease in kidney function
and/or urine output is observed, which may result in the imbalance of water, electrolytes and …

Background The association between intravitreal anti-vascular endothelial growth factor
(anti-VEGF) treatment and the risk of major thromboembolic adverse events (TAEs) remains …

The introduction of novel molecularly targeted therapies in the last 2 decades has
significantly improved the patient survival compared to standard conventional …