Tomato (Solanum lycopersicum L.) in the service of biotechnology

A Gerszberg, K Hnatuszko-Konka, T Kowalczyk… - Plant Cell, Tissue and …, 2015 - Springer
Originating in the Andes, the tomato (Solanum lycopersicum L.) was imported to Europe in
the 16th century. At present, it is an important crop plant cultivated all over the world, and its …

Plant‐made vaccines for humans and animals

EP Rybicki - Plant biotechnology journal, 2010 - Wiley Online Library
The concept of using plants to produce high‐value pharmaceuticals such as vaccines is 20
years old this year and is only now on the brink of realisation as an established technology …

Plants as bioreactors: recent developments and emerging opportunities

AK Sharma, MK Sharma - Biotechnology advances, 2009 - Elsevier
In recent years, the use of plants as bioreactors has emerged as an exciting area of research
and significant advances have created new opportunities. The driving forces behind the …

Plant-made vaccines against viral diseases in humans and farm animals

H Su, A Van Eerde, E Rimstad, R Bock… - Frontiers in plant …, 2023 - frontiersin.org
Plants provide not only food and feed, but also herbal medicines and various raw materials
for industry. Moreover, plants can be green factories producing high value bioproducts such …

Plants as bioreactors for the production of vaccine antigens

S Tiwari, PC Verma, PK Singh, R Tuli - Biotechnology advances, 2009 - Elsevier
Plants have been identified as promising expression systems for commercial production of
vaccine antigens. In phase I clinical trials several plant-derived vaccine antigens have been …

Plant-derived recombinant vaccines against zoonotic viruses

G Zahmanova, K Takova, R Valkova, V Toneva… - Life, 2022 - mdpi.com
Emerging and re-emerging zoonotic diseases cause serious illness with billions of cases,
and millions of deaths. The most effective way to restrict the spread of zoonotic viruses …

Mucosal HIV transmission and vaccination strategies through oral compared with vaginal and rectal routes

M Yu, M Vajdy - Expert opinion on biological therapy, 2010 - Taylor & Francis
Importance of the field: There are currently over thirty million people infected with HIV and
there are no vaccines available to prevent HIV infections or disease. The genitourinary …

Production of Pharmaceutical Proteins in Solanaceae Food Crops

MM Rigano, G De Guzman, AM Walmsley… - International journal of …, 2013 - mdpi.com
The benefits of increased safety and cost-effectiveness make vegetable crops appropriate
systems for the production and delivery of pharmaceutical proteins. In particular …

Functional characterization of a strong promoter of the early light-inducible protein gene from tomato

V Timerbaev, S Dolgov - Planta, 2019 - Springer
Main conclusion The tomato ELIP gene promoter is mainly active in the ripening fruit.
Considering its high activity, the promoter could be used for molecular breeding of plants in …

A multisite gateway‐based toolkit for targeted gene expression and hairpin RNA silencing in tomato fruits

LH Estornell, D Orzáez, L López‐Peña… - Plant biotechnology …, 2009 - Wiley Online Library
A collection of fruit promoters, reporter genes and protein tags has been constructed in a
triple‐gateway format, a recombination‐based cloning system that facilitates the tandem …